The Prognosis of Gastroschisis and Omphalocele

E. Jwa, S. Kim, D. Kim, Jihee Hwang, J. Namgoong, I. Kim
{"title":"The Prognosis of Gastroschisis and Omphalocele","authors":"E. Jwa, S. Kim, D. Kim, Jihee Hwang, J. Namgoong, I. Kim","doi":"10.13029/JKAPS.2014.20.2.38","DOIUrl":null,"url":null,"abstract":"Purpose: Gastroschisis and omphalocele are major anterior abdominal wall defects. The purpose of this study was to analyze the clinical differences and mortalities of gastroschisis and omphalocele in Asan Medical Center. Methods: A retrospective review of the medical records was conducted of 103 cases of gastroschisis and omphalocele from September 1989 to February 2013 in Asan Medical Center in Korea. Results: There were 43 cases (41.7%) of gastroschisis and 60 cases (58.3%) of omphalocele. There was a female predominance in both gastroschisis (60.5%) and omphalocele (58.3%). The average gestational age at delivery was 36.7±0.4 weeks for both groups. The mean birth weights were 2,381.9±80.6 g for gastroschisis and 2,779.4±82.8 g for omphalocele (p=0.001). Mean maternal ages in the gastroschisis and omphalocele groups were 27.5±0.7 years and 30.5±0.7 years, respectively (p=0.002). Associated malformations were documented in 13 infants (30.2%) with gastroschisis and 46 infants (76.7%) with omphalocele (p<0.001). All of gastroschisis patients except one underwent surgery including 31 primary repairs and 11 staged repairs. Fifty-two infants with omphalocele underwent surgery−primary repair in 41 infants and staged repair in 11 infants. Among 103 cases, 19 cases (18.4%) expired. Mortality rates of gastroschisis and omphalocele were 23.3% (10/43 cases) and 15.0% (9/60 cases), respectively (p=0.287). The main causes of death were abdominal compartment syndrome (6/10 cases) in gastroschisis, respiratory failure (4/9 cases) and discharge against medical advice (4/9 cases) in omphalocele. Conclusion: Gastroschisisis was associated with younger maternal age and lower birth weight than omphalocele. Associated malformations were more common in omphalocele. The mortality rates did not make a statistical significance. This might be the improvement of treatment of cardiac anomalies, because no patient died from cardiac dysfunction in our study. Furthermore, abdominal compartment syndrome might be the main cause of death in gastroschisis.","PeriodicalId":164943,"journal":{"name":"Journal of Korean Association of Pediatric Surgeons","volume":"122 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Korean Association of Pediatric Surgeons","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.13029/JKAPS.2014.20.2.38","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4

Abstract

Purpose: Gastroschisis and omphalocele are major anterior abdominal wall defects. The purpose of this study was to analyze the clinical differences and mortalities of gastroschisis and omphalocele in Asan Medical Center. Methods: A retrospective review of the medical records was conducted of 103 cases of gastroschisis and omphalocele from September 1989 to February 2013 in Asan Medical Center in Korea. Results: There were 43 cases (41.7%) of gastroschisis and 60 cases (58.3%) of omphalocele. There was a female predominance in both gastroschisis (60.5%) and omphalocele (58.3%). The average gestational age at delivery was 36.7±0.4 weeks for both groups. The mean birth weights were 2,381.9±80.6 g for gastroschisis and 2,779.4±82.8 g for omphalocele (p=0.001). Mean maternal ages in the gastroschisis and omphalocele groups were 27.5±0.7 years and 30.5±0.7 years, respectively (p=0.002). Associated malformations were documented in 13 infants (30.2%) with gastroschisis and 46 infants (76.7%) with omphalocele (p<0.001). All of gastroschisis patients except one underwent surgery including 31 primary repairs and 11 staged repairs. Fifty-two infants with omphalocele underwent surgery−primary repair in 41 infants and staged repair in 11 infants. Among 103 cases, 19 cases (18.4%) expired. Mortality rates of gastroschisis and omphalocele were 23.3% (10/43 cases) and 15.0% (9/60 cases), respectively (p=0.287). The main causes of death were abdominal compartment syndrome (6/10 cases) in gastroschisis, respiratory failure (4/9 cases) and discharge against medical advice (4/9 cases) in omphalocele. Conclusion: Gastroschisisis was associated with younger maternal age and lower birth weight than omphalocele. Associated malformations were more common in omphalocele. The mortality rates did not make a statistical significance. This might be the improvement of treatment of cardiac anomalies, because no patient died from cardiac dysfunction in our study. Furthermore, abdominal compartment syndrome might be the main cause of death in gastroschisis.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
腹裂和脐膨出的预后
目的:腹裂和脐膨出是腹壁主要的前壁缺损。本研究旨在分析峨山医疗中心胃裂与脐膨出的临床差异及病死率。方法:回顾性分析1989年9月至2013年2月在韩国峨山医院收治的103例胃裂及脐膨出患者的病历资料。结果:胃裂43例(41.7%),脐膨出60例(58.3%)。腹裂(60.5%)和脐膨出(58.3%)均以女性为主。两组平均胎龄为36.7±0.4周。胃裂的出生体重为2381.9±80.6 g,脐膨出的出生体重为2779.4±82.8 g (p=0.001)。腹裂组和脐膨出组产妇平均年龄分别为27.5±0.7岁和30.5±0.7岁(p=0.002)。胃裂患儿13例(30.2%),脐膨出患儿46例(76.7%)(p<0.001)。所有胃裂患者除1例外均行手术,其中31例为一期修复,11例为分期修复。52名患有脐膨出的婴儿接受了手术- 41名婴儿进行了一次修复,11名婴儿进行了分阶段修复。103例中有19例(18.4%)过期。胃裂和脐膨出的死亡率分别为23.3%(10/43例)和15.0%(9/60例)(p=0.287)。胃裂的主要死亡原因为腹膜隔室综合征(6/10),脐膨出的主要死亡原因为呼吸衰竭(4/9)和不遵医嘱出院(4/9)。结论:与脐膨出相比,腹裂与产妇年龄小、出生体重低有关。相关畸形在脐膨出中更为常见。死亡率没有统计学意义。这可能是心脏异常治疗的进步,因为在我们的研究中没有患者死于心功能障碍。此外,腹隔室综合征可能是胃裂的主要死亡原因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Is Preoperative Ultrasonography Necessary in Pediatric Inguinal Hernia Congenital Esophageal Stenosis in Children: From Etiology to Prognosis Bile Duct Stricture and Intrahepatic Cystic Formation after Abdominal Injury due to Child Abuse: A Case Report Santulli Enterostomy: A Considerable Method for Patients Who Require Proximal Enterostomy Is Barium Enema Reliable for the Diagnosis of Total Colonic Aganglionosis
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1