{"title":"Crypt cell population changes in the mouse jejunum during injury and repair after whole-body gamma irradiation.","authors":"K Nandchahal","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Adult Swiss albino mice were exposed to 4.5 Gy, 9.0 Gy and 12.0 Gy of 60Co gamma rays and post-irradiation variations in the crypt cell population of jejunum were studied. In all the three exposure groups, a significant decrease in cellularity was observed on day 1. With the beginning of recovery crypt cell population tended to increase and gradually approached normal value by day 8 and 14 in mice exposed to 4.5 Gy and 9.0 Gy respectively. In mice exposed to 12.0 Gy normal value was never attained.</p>","PeriodicalId":76404,"journal":{"name":"Radiobiologia, radiotherapia","volume":"31 4","pages":"337-9"},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiobiologia, radiotherapia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Adult Swiss albino mice were exposed to 4.5 Gy, 9.0 Gy and 12.0 Gy of 60Co gamma rays and post-irradiation variations in the crypt cell population of jejunum were studied. In all the three exposure groups, a significant decrease in cellularity was observed on day 1. With the beginning of recovery crypt cell population tended to increase and gradually approached normal value by day 8 and 14 in mice exposed to 4.5 Gy and 9.0 Gy respectively. In mice exposed to 12.0 Gy normal value was never attained.