Physiology of Geriatrics

C. Matadial
{"title":"Physiology of Geriatrics","authors":"C. Matadial","doi":"10.2310/anes.18397","DOIUrl":null,"url":null,"abstract":"The aging population is growing and life expectancy is prolonged. The elderly population is able to enjoy prolonged life with good management of their chronic conditions. Many elderly do not have medical conditions but we still see a decline in their organ function and physiologic reserve that weighs in on their daily living. As well these changes in anatomy, physiology and chemistry puts them at risk of developing medical conditions and experience adverse outcomes during surgery and anesthesia. The central nervous, cardiovascular, respiratory, hepatic and renal systems all work together and are affected as a whole with aging causing physiologic changes but also compensatory mechanisms. In this review we will study the aging physiology of the body and touch on its implications in anesthesia.\nThis review contains 5 figures, 3 tables, and  55 references.\nKeywords: Healthy aging, age-related changes, Postoperative cognitive dysfunction, diastolic dysfunction, vascular stiffening, ventricular arterial coupling, Chronic obstructive pulmonary disease, Spirometry, Glomerular Filtration Rate, hallmarks of aging","PeriodicalId":345138,"journal":{"name":"DeckerMed Anesthesiology","volume":"70 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"DeckerMed Anesthesiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2310/anes.18397","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract

The aging population is growing and life expectancy is prolonged. The elderly population is able to enjoy prolonged life with good management of their chronic conditions. Many elderly do not have medical conditions but we still see a decline in their organ function and physiologic reserve that weighs in on their daily living. As well these changes in anatomy, physiology and chemistry puts them at risk of developing medical conditions and experience adverse outcomes during surgery and anesthesia. The central nervous, cardiovascular, respiratory, hepatic and renal systems all work together and are affected as a whole with aging causing physiologic changes but also compensatory mechanisms. In this review we will study the aging physiology of the body and touch on its implications in anesthesia. This review contains 5 figures, 3 tables, and  55 references. Keywords: Healthy aging, age-related changes, Postoperative cognitive dysfunction, diastolic dysfunction, vascular stiffening, ventricular arterial coupling, Chronic obstructive pulmonary disease, Spirometry, Glomerular Filtration Rate, hallmarks of aging
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老年生理学
人口老龄化加剧,预期寿命延长。老年人口能够享受延长寿命与良好的管理他们的慢性病。许多老年人没有疾病,但我们仍然看到他们的器官功能和生理储备的下降,这影响了他们的日常生活。此外,这些解剖学、生理学和化学上的变化也使他们面临发展疾病的风险,并在手术和麻醉期间经历不良后果。中枢神经系统、心血管系统、呼吸系统、肝脏和肾脏系统都协同工作,作为一个整体受到影响,衰老引起生理变化,但也有代偿机制。在这篇综述中,我们将研究身体的衰老生理及其在麻醉中的意义。本综述包含5个图,3个表,55篇参考文献。关键词:健康老龄化、年龄相关变化、术后认知功能障碍、舒张功能障碍、血管硬化、心室动脉耦合、慢性阻塞性肺疾病、肺活量测定法、肾小球滤过率、衰老特征
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