A network-based analysis of medical information extracted from electronic medical records

R. Reátegui, S. Ratté, Estefanía Bautista-Valarezo, J. F. Beltran-Valdivieso
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Abstract

Clinical notes constitute a rich source of medical information that could be useful in identifying graphs of patients with similar characteristics. Network-based approaches permit to visualize associations between medical entities and to infer medical knowledge. This paper aims to apply such an approach to identify the graphs of obesity patients as well as relationships between diseases and treatments extracted from discharge summaries. Two experiments were designed. In the first experiment, a 412-node graph representing patients was constructed to identify patient groups. Graphs were obtained with the modularity function. In the second, some bipartite graphs were constructed to identify disease-treatment relationships from patient graphs. The results were congruent in both experiments. Patient graphs corresponding to obese patients with diseases derived from a metabolic problem were identified; some had infectious diseases, while others had diseases derived from a mechanical problem. Furthermore, graphs of diseases and treatments related to obesity could be observed. This work identified obesity-patient graphs and relationships between diseases and treatments based on a network approach, which took into account information extracted from clinical notes.
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从电子病历中提取医疗信息的基于网络的分析
临床记录构成了丰富的医学信息来源,可用于识别具有相似特征的患者图表。基于网络的方法允许可视化医学实体之间的关联,并推断医学知识。本文旨在应用这种方法来识别肥胖症患者的图表以及从出院摘要中提取的疾病与治疗之间的关系。设计了两个实验。在第一个实验中,我们构建了一个412节点的患者图来识别患者群体。利用模块化函数得到图形。在第二部分中,构造了一些二分图来从患者图中识别疾病-治疗关系。两个实验的结果是一致的。确定了患有代谢问题引起的疾病的肥胖患者的患者图;一些人患有传染病,而另一些人的疾病是由机械问题引起的。此外,还可以观察到与肥胖有关的疾病和治疗的图表。这项工作基于网络方法确定了肥胖患者的图表以及疾病和治疗之间的关系,该方法考虑了从临床记录中提取的信息。
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