[Comparative study of the tumor regression rate of 127 uveal melanomas irradiated with 106 Ru/106 Rh. Attempted analysis of the correlations between per-operative cytology and histopathology of the enucleated eye and the tumoral regression on the one hand, and general prognosis on the other hand].

J D Grange, S Thacoor, B Bievelez, B Jean-Louis, B Baute, J P Gérard, I Sentenac, B Fontanière, C Bailly
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Abstract

A study of the speed of tumor regression in 127 uveal melanomas treated with beta-rays brachyterapy, since June 1983, allows a division into 2 groups: radiosensitive forms with a volume less than 50% in the following year, and radioresistant forms. Correlation between radio sensitivity and tumor cell type were obtained with intraoperative cytopunction, and showed the prevalence of epithelioid type. The results of enucleation indicate the prevalence of fusiform type inside the radioresistant tumor group. No precise correlation could be brought between death and the previous data, the most important negative criteria being the level of initial tumor height equal or superior to 7 mm.

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[106 Ru/106 Rh辐照127例葡萄膜黑色素瘤肿瘤消退率的比较研究。]试图分析去核眼手术前细胞学和组织病理学与肿瘤消退及一般预后的相关性。
自1983年6月以来,对127例接受近距离射线治疗的葡萄膜黑色素瘤的肿瘤消退速度进行了研究,将其分为两组:放射敏感型(次年体积小于50%)和放射耐药型。放射敏感性与肿瘤细胞类型及术中细胞功能的相关性,显示上皮样类型的患病率。去核结果表明,在放射耐药肿瘤组中梭形型的流行。死亡与既往数据之间没有精确的相关性,最重要的阴性标准是初始肿瘤高度等于或大于7mm。
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