Simulation Study of a Dialysis Equivalence Model for Wearable Artificial Kidney

Abstract

Chronic kidney disease is a global health problem and wearable artificial kidney is the future trend. The size of wearable artificial kidney depends on the size of dialysis volume. In this paper, based on the current peritoneal anatomy and physiology, we investigated a modeling analysis study of the dialysis equivalent, which was based on the three-pores model describing the transport of substances across the membrane. From the results, it was found that as the volume of dialysate becomes smaller, the maximum volume of dialysate appears earlier. It provides the basis and ideas for the design of the volume size of the wearable artificial kidney.