[Kyrle disease--a case report].

Abstract

Based on a case of our own observation, we present the characteristic features of a rare skin disease: hyperkeratosis follicularis et parafollicularis in cutem penetrans, i.e. Kyrle's disease. The clinical picture shows follicular and interfollicular hyperkeratotic horn-like plugs with a typical distribution pattern. The classical histological features are epidermolysis and hyperkeratoses advancing towards the dermis. Today, this disease is regarded as a genodermatosis with recessive heredity and is best treated with systemic and topical application, resp., of vitamin A acid.