Evaluation of respiratory Failure in Patients with Chronic Obstructive Pulmonary disease

B. Shah, H. Shrivastava, A. Julka, M. Dubey, Shubham Mishra
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Abstract

Objectives: - The aim of the present study is to evaluate the clinical profile, investigations, treatment protocol and the response to the therapy in patient of COPD presenting with Respiratory failure. Materials and Methods: - All those patient with COPD with respiratory failure admitted in IPD in department of Respiratory Medicine R. D. Gardi Medical College Ujjain included in the study. Patients were evaluated by a detailed history, clinical examination, chest radiograph, arterial blood gas analysis and relevant blood investigation and were put on treatment. All the information was written in a proforma and the results were analysed. Results: - Majority of the patients were males (83.3%) with mean age of 65 years. In our study, the most common risk factor for COPD with respiratory failure was found to be smoking (80%). Nearly 70% cases were having type 2 respiratory failure. The main causes of exacerbations were bronchospasm(88.3%) and secondary infection (68.4%). 65% of the patients were discharged on room air with medical treatment, 23.3% patients were discharge on home oxygen with medical treatment, 3.33% patients discharged on NIV along with medical treatment and 5 patients died during hospitalization. Conclusion: - It is very important to take holistic approach toward COPD patient with respiratory failure. Early diagnosis, prompt treatment, pulmonary rehabilitation and vaccination are mainstay of management modalities and to prevent further exacerbation in patients.  
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慢性阻塞性肺疾病患者呼吸衰竭的评价
目的:本研究的目的是评估慢性阻塞性肺病合并呼吸衰竭患者的临床特征、调查、治疗方案和治疗反应。材料与方法:所有在Ujjain Gardi医学院呼吸内科IPD住院的COPD合并呼吸衰竭患者纳入研究。通过详细的病史、临床检查、胸片、动脉血气分析及相关血液检查对患者进行评估,并给予治疗。所有的信息都以形式写下来,并对结果进行了分析。结果:患者以男性为主(83.3%),平均年龄65岁。在我们的研究中,COPD合并呼吸衰竭最常见的危险因素是吸烟(80%)。近70%的病例有2型呼吸衰竭。加重的主要原因是支气管痉挛(88.3%)和继发感染(68.4%)。室内空气出院者占65%,家庭吸氧出院者占23.3%,无创通气出院者占3.33%,住院期间死亡5例。结论:对慢性阻塞性肺病合并呼吸衰竭患者采取综合治疗是非常重要的。早期诊断、及时治疗、肺部康复和疫苗接种是管理模式的主要内容,可防止患者病情进一步恶化。
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