Comparative Evaluation Of Low Dose Hyperbaric Bupivacaine With Or Without Fentanyl In Spinal Anaesthesia For Caesarean Section In Patients With Pregnancy Induced Hypertension

Faisal Sheikh, Mubasher Ahmed, Mohamad Ommid, S. Gurcoo, N. Shakoor, Sheeba Nazir, Gousia Nisa
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引用次数: 6

Abstract

Neuraxial administration of opioid’s along with local anesthetics improve the quality of intraoperative analgesia and also provides postoperative pain relief for longer duration. The present study was conducted to study and compare the effects of bupivacaine alone and its combination with fentanyl used intrathecally in parturients with PIH. 50 ASA grade II patients with PIH defined as blood pressure between 140-160/ 90-110 mmHg without proteinuria were selected and divided into 2 groups as Group (I)-Bupivacaine and Group (II)BupivacaineFentanyl group. Haemodynamic variables like systolic and diastolic blood pressure, heart rate were recorded every 2 minutes upto delivery of baby and then every 5 minutes until end of surgery. Sensory block and motor block alongwith side effects were recorded. Pain was evaluated using visual analogue scale and neonatal outcome assessed using APGAR scoring. The highest sensory level achieved in bupivacaine-fentanyl group was higher than in the group receiving plain bupivacaine. The time taken for sensory regression to T12 and duration of analgesia was longer in the Bupivacaine-Fentanyl group. We conclude the combination group prolongs the duration of sensory spinal block, increases the duration of analgesia without increasing the duration of motor block, does not cause any significant side effects and provides stable haemodynamic conditions without fetal or maternal compromise.
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低剂量高压布比卡因加芬太尼或不加芬太尼用于妊高征剖宫产脊柱麻醉的比较评价
阿片类药物与局部麻醉剂的轴向给药提高了术中镇痛的质量,也提供了术后更长时间的疼痛缓解。本研究旨在研究和比较布比卡因单用和芬太尼联用对妊高围产妇的影响。选择血压在140-160/ 90-110 mmHg且无蛋白尿的ASA II级PIH患者50例,分为(I)布比卡因组和(II)布比卡因芬太尼组。在分娩前每2分钟记录一次收缩压、舒张压、心率等血流动力学变量,然后每5分钟记录一次,直到手术结束。记录感觉阻滞、运动阻滞及副作用。采用视觉模拟量表评估疼痛,采用APGAR评分评估新生儿预后。布比卡因-芬太尼组的最高感觉水平高于普通布比卡因组。布比卡因-芬太尼组感觉恢复至T12所需时间和镇痛持续时间更长。我们认为,联合组延长了感觉脊髓阻滞的持续时间,增加了镇痛的持续时间,而不增加运动阻滞的持续时间,没有引起任何明显的副作用,并提供了稳定的血流动力学条件,没有损害胎儿或母体。
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