[Studies of natural killer cell cytotoxicity against human chondrocytes in patients with articular arthritic changes complicated by psoriasis and systemic scleroderma].

IF 0.5 Q4 DERMATOLOGY Przeglad dermatologiczny Pub Date : 1990-11-01
J Malejczyk, S Majewski, W Gliński, L Rudnicka, M Malejczyk
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引用次数: 0

Abstract

The natural killer (NK) activity against fetal chondrocytes was studied in patients with psoriasis and systemic sclerosis. It was shown that the cell responsible for the cytotoxic effect is a lymphocyte CD16+, CD2-. In patients with arthritic psoriasis NK activity against chondrocytes was significantly higher than in other psoriasis patients or in healthy controls. Preliminary studies show that the NK activity against chondrocytes is decreased in patients with systemic sclerosis.

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自然杀伤细胞对关节关节炎合并银屑病和系统性硬皮病患者软骨细胞的毒性研究。
研究了银屑病和系统性硬化症患者对胎儿软骨细胞的自然杀伤(NK)活性。结果表明,产生细胞毒性作用的细胞是CD16+、CD2-淋巴细胞。关节炎性银屑病患者抗软骨细胞NK活性明显高于其他银屑病患者或健康对照。初步研究表明,NK细胞对软骨细胞的活性在系统性硬化症患者中降低。
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来源期刊
CiteScore
0.80
自引率
14.30%
发文量
9
审稿时长
12 weeks
期刊介绍: Przegląd Dermatologiczny (ang. Dermatological Review) is a bimonthly magazine of the Polish Dermatological Association. It publishes original (clinical and experimental) papers, review papers, care reports, reports from congresses, reviews of books, announcements, letters to the editor and special papers (requested by the editors), concerning selected dermatological and interdisciplinary issues. Papers sent to the editor are reviewed.
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