[Spontaneous course of chronic gastritis in corpus and antrum--is there a regression?].

G Wolff, A Raabe, K Erler, G Rogalla
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Abstract

In 148 patients (medium of 59, 1 years) we investigated the natural history of chronic gastritis within 1-7 years (average of 5.9 years). We performed two biopsies, but in 35 cases 3 or 4 biopsies. In most patients the histological picture was not changed. In superficial gastritis of the body we observed a regression more often than a progression. Regression of atrophic gastritis was see in body and antrum. The rate of regression was higher in cases with 3 or 4 biopsies and with a longer interval of observation. The frequency of regression was higher than awaited according to simultaneous biopsies (criticism of method). There was no difference of rate of regression in various age groups and in various diagnosis (gastric or duodenal ulcer). In gastritis Type B the regression was more seldom than in gastritis Type a or type AB. For spontaneous regression no cause was found.

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慢性胃炎自发性病程:是否有消退?
148例患者(中位数为59,1岁)在1-7年内(平均5.9年)调查慢性胃炎的自然史。我们做了两次活检,但在35例中有3或4次活检。大多数患者的组织学图没有改变。在身体的浅表性胃炎中,我们观察到退行多于进展。萎缩性胃炎在机体及胃窦均有消退。在3次或4次活检和观察间隔较长的情况下,回归率较高。根据同时活检,回归的频率高于预期(方法批评)。不同年龄组和不同诊断(胃溃疡或十二指肠溃疡)的退化率无差异。B型胃炎复发较a型和AB型胃炎少见,自发性复发无原因。
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