Reccurence of ovarian endometriotic cyst after cystectomy

Hiroko Nakamura, Kiyoko Kato, S. Uchida, R. Tsunematsu, A. Isobe
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Abstract

Objective: To evaluate risk factors which are associated with recurrence of endometriotic cysts after cystectomy.Method: Fifty-seven patients who had a minimum of 6 months of observation after cystectomies for endometriotic cyst were studied retrospectively. Recurrence was defined as the presence of an endometriotic cyst > 2 cm in size on transvaginal ultrasonogram during the post-operative follow-up period. We evaluated nine variables (age, laparoscopic surgery/laparotomy, size of the largest cyst, laterality, findings of transvaginal ultrasonogram, serum CA-125 levels, revised American Society for Reproductive Medicine [r-ASRM] classification, and pre- and post-operative medical treatment) to assess the effects on the recurrence using logistic regression analysis.Result: The overall rate of recurrence was 17.5% (10/57). The cumulative rate of recurrence over 60 months was 32.1%. Laparoscopic treatment had a higher recurrence rate than laparotomy (p<0.05).The statistically significant factor that was associated with a higher recurrence rate was pre-operative medical treatment (p=0.02).Conclusion: Pre-operative medical treatment of endometriotic cysts is associated with a higher recurrence rate after cystectomy.
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卵巢子宫内膜异位囊肿切除术后的复发
目的:探讨子宫内膜异位囊肿切除术后复发的相关危险因素。方法:回顾性分析57例子宫内膜异位症囊肿切除术后观察时间不少于6个月的临床资料。复发定义为术后随访期间经阴道超声检查发现子宫内膜异位囊肿> 2cm。我们评估了9个变量(年龄、腹腔镜手术/剖腹手术、最大囊肿的大小、侧边性、经阴道超声检查结果、血清CA-125水平、修订的美国生殖医学学会[r-ASRM]分类、术前和术后用药),使用logistic回归分析来评估对复发的影响。结果:总复发率为17.5%(10/57)。60个月累计复发率为32.1%。腹腔镜治疗的复发率高于剖腹手术(p<0.05)。与复发率相关的有统计学意义的因素是术前治疗(p=0.02)。结论:术前药物治疗与子宫内膜异位囊肿切除术后复发率高有关。
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