Use of Waste Salmon Bones as a Biomaterial

Merve Bas, S. Dağlilar, C. Kalkandelen, O. Gunduz
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Abstract

In the presented study; Hydroxyapatite (HA) used in many areas such as filling of cavities, bone tissue treatments, chin-face, orthopedic and dental surgeries, was obtained from waste salmon fish bones. Instead of producing chemically in a laboratory environment, hard tissue waste of natural resources was used. As trace elements such as magnesium, zinc, and strontium in the structure of natural resources support bone formation, waste salmon fish bones, which are a natural source, were preferred as raw materials. Other advantages include being easy to access raw materials, cheap and environmentally friendly. HA was obtained from salmon bones by the thermal calcination method. The obtained pure salmon hydroxyapatites were sintered at different temperatures, and the effect of changing sintering temperature on the density, microhardness, compressive strength, and elasticity module in the material was investigated. Crystal phase analysis of salmon hydroxyapatite powder and thermal analysis up to a certain temperature were made. MTT cytotoxicity test was performed to measure whether the materials were toxic. This study has the potential to contribute to the development of biomaterial studies for bone repair.
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利用废鲑鱼骨作为生物材料
在本研究中;羟基磷灰石(HA)从废弃的鲑鱼鱼骨中提取,用于许多领域,如填充蛀牙,骨组织治疗,下巴面部,骨科和牙科手术。利用自然资源的硬组织废物代替在实验室环境中化学生产。由于天然资源结构中的镁、锌、锶等微量元素支持骨的形成,因此作为天然来源的废鲑鱼鱼骨是首选的原料。其他优势还包括原材料容易获取、价格便宜且对环境友好。采用热煅烧法从鲑鱼骨中获得透明质酸。将所得的三文鱼羟基磷灰石在不同温度下进行烧结,研究了烧结温度对材料密度、显微硬度、抗压强度和弹性模量的影响。对三文鱼羟基磷灰石粉进行了晶相分析和一定温度下的热分析。采用MTT细胞毒性试验检测材料是否有毒性。本研究对骨修复生物材料研究的发展具有潜在的促进作用。
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