[Study of esophageal motility in diabetic patients using the scintigraphic method].

R Innocenti, A Castagnoli
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Abstract

Oesophagus scintigraphy with 99mTc was used to evaluate oesophageal motility in a group of 23 diabetics without symptoms of autonomic neuropathy (AN). 11 patients were found to have a pathological response to the cardiovascular AN nerve tests. This group of diabetic patients with asymptomatic AN had a high frequency of esophageal dysfunction and a pattern of motor change characterized by uncoordinated movements compared with the group of diabetics without AN and with controls. No correlation between duration of diabetes, insulin dependence, presence of peripheral neuropathy (PN) and motor changes was found. The authors conclude asserting that oesophagus scintigraphy, owing to its sensibility, can lead to an early diagnosis of oesophageal dysfunction in diabetics when symptoms of NA are not yet observed.

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[用闪烁图法研究糖尿病患者食管运动]。
采用99mTc食管显像评价23例无自主神经病变(AN)症状的糖尿病患者的食管运动。11例患者对心血管AN神经试验有病理反应。与没有AN的糖尿病患者和对照组相比,这组无症状AN的糖尿病患者有高频率的食管功能障碍和以不协调运动为特征的运动改变模式。糖尿病病程、胰岛素依赖、周围神经病变(PN)和运动改变之间无相关性。作者总结道,由于其敏感性,食道显像可以在尚未观察到NA症状的糖尿病患者中早期诊断食道功能障碍。
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