Role of Platelet Rich Plasma in Mucosal Healing After Nasal Surgeries

Abstract

Aim: To Demonstrate Role Of Platelet Rich Plasma In Mucosal Healing After Nasal Surgeries. Patiants and Methods: This prospective study was conducted at Otolaryngology, Head and Neck surgery department, The study was approved by the Institutional Review Board at Minia University. During the period from 2021 to 2022, we selected, operated, and followed up 200 patients who had bilateral symmetrical nasal surgery.The study participants were recruited from patients with nasal disease attending outpatient clinic and required nasal surgery. The patients were randomly classified into two groups, with 100 patients in each group. Results: Autologous PRP application accelerates mucosal healing after nasal surgeries.This study included 200 subjects divided into two groups There was a significant difference in the occurrence of synechia between group 1 (study group) and group 2 (control group) (p=0.034).In study group synechia occurred in 8 patients it was mild and reliefed by repeated packing,while in control group synechia occurred in 14 and was more length and needed excision under local anathesia with repeated packing. Conclusion: In conclusion, prp is a simple and effective method, and application of prp mucosal wound can be healed faster in early period after nasal surgeries. It also decrease postoperative early period of pain,bleeding and synechia that enhance the quality of life for patient after nasal surgery.