[The dose precision of PMSG in young and old sows in the process of biotechnical ovulation synchronization. 1. Comparison of diagnostic laparotomy].

J Bergfeld, B Rubo, M Krey, G George
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Abstract

Treatment was applied, on two farms, to 272 gilts and 169 adult sows, 24 hours after discontinuation of Suisynchron application to the gilts or weaning of piglets of adult sows. Included were 600, 800 or 1,000 IU of PMSG for the gilts and 750, 1,000 oder 1,250 IU of the same batch (Pregmagon-Dessau) for the adult sows for ovarian stimulation. This was followed by application of 500 IU of HCG to the gilts or 300 micrograms Gn-RH vet. "Berlin-Chemie" + 300 IU HCG to the adult sows for synchronised ovulation. Laparotomy was performed on the gilts on the fifth day from PMSG application and on the adult sows on the fourth day. Average ovariotropic stimulation was "mild" in response to lower doses (14.8 follicles in gilts and 20.4 follicles in adult sows) but was "pronounced" in response to medium doses (19.4 or 22.7 follicles, respectively). The pharmacological concept of "mild" exogenic ovarian stimulation by low dosage at the threshold of effectiveness should deserve more attention, last but not least, for breeding aspects. The two groups of animals on both farms differed considerably from one another with regard to reactivity, which cannot be etiologically interpreted for the time being.

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[生物技术促排卵过程中,幼母猪和老母猪PMSG的剂量精度。]1. 诊断性剖腹手术的比较[j]。
在两个猪场,对272头后备母猪和169头成年母猪进行了处理,处理时间是在对后备母猪或成年母猪断奶仔猪停用Suisynchron 24小时后。包括对后备母猪的600、800或1,000 IU的PMSG和对成年母猪的750、1,000或1,250 IU的PMSG (Pregmagon-Dessau)用于卵巢刺激。随后在后备母猪中应用500 IU HCG或300微克Gn-RH。“柏林化学”+ 300 IU HCG给成年母猪同步排卵。应用PMSG第五天对后备母猪进行剖腹手术,第四天对成年母猪进行剖腹手术。低剂量(后备母猪14.8个卵泡和成年母猪20.4个卵泡)的平均促卵巢刺激“轻微”,但中等剂量(分别为19.4和22.7个卵泡)的促卵巢刺激“明显”。在有效阈值下低剂量“轻度”外源性卵巢刺激的药理学概念值得更多关注,最后但并非最不重要的是在育种方面。两个农场的两组动物在反应性方面存在很大差异,目前还不能从病因学上解释这一点。
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