Undisclosed Placebo Trials in Clinical Practice: Undercover Beneficence or Unwarranted Deception?

Q4 Medicine Narrative inquiry in bioethics Pub Date : 2023-03-01 DOI:10.1353/nib.2023.0017
Daniel Edward Callies
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Abstract

A placebo is an intervention that is believed to lack specific pharmacological or physiological efficacy for a patient's condition. While placebo-controlled trials are considered the gold standard when it comes to researching and testing new pharmacological treatments, the use of placebos in clinical practice is more controversial. The focus of this case study is an undisclosed placebo trial used as an attempt to diagnose a patient's complex and unusual symptomology. In this case, the placebo was used not just as a treatment, but as a diagnostic intervention in order to determine the best course of treatment for a patient. Could the deceptive use of a placebo be justified in clinical practice on the grounds of beneficence?
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临床实践中未公开的安慰剂试验:秘密的善行还是无端的欺骗?
安慰剂是一种干预措施,被认为对患者的病情缺乏特定的药理学或生理学功效。虽然安慰剂对照试验被认为是研究和测试新药物治疗的黄金标准,但在临床实践中使用安慰剂更具争议性。本案例研究的重点是一项未公开的安慰剂试验,用于诊断患者复杂和不寻常的症状。在这种情况下,安慰剂不仅仅是作为一种治疗手段,而是作为一种诊断干预手段,以确定对患者的最佳治疗方案。在临床实践中,以慈善为理由,欺骗性使用安慰剂是否合理?
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来源期刊
Narrative inquiry in bioethics
Narrative inquiry in bioethics Medicine-Medicine (all)
CiteScore
0.20
自引率
0.00%
发文量
27
期刊介绍: Narrative Inquiry in Bioethics (NIB) is a unique journal that provides a forum for exploring current issues in bioethics through personal stories, qualitative and mixed-methods research articles, and case studies. NIB is dedicated to fostering a deeper understanding of bioethical issues by publishing rich descriptions of complex human experiences written in the words of the person experiencing them. While NIB upholds appropriate standards for narrative inquiry and qualitative research, it seeks to publish articles that will appeal to a broad readership of healthcare providers and researchers, bioethicists, sociologists, policy makers, and others. Articles may address the experiences of patients, family members, and health care workers.
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