Endocrine Disrupting Chemicals and their Role in Cancer-A review

Odangowei Inetiminebi Ogidi, Akpofiniere Monica Tawariowei
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Abstract

Endocrine-disrupting chemicals (EDCs), which are environmentally prevalent compounds, have the ability to interact with the body's endocrine system and thus exert detrimental effects on human health. Despite persistent concerns over public health, endocrine-disrupting chemicals (EDCs) remain integral components of commonplace consumer products, rendering them ubiquitous pollutants for individuals. In light of the numerous epidemiological and experimental studies that have established a connection between endocrine-disrupting chemicals and adverse effects on human health, there has been an increased emphasis on mitigating human exposure to these compounds. There exists a correlation between endocrine-disrupting drugs and adverse impacts on human health, as well as an elevated susceptibility to hormone-sensitive cancers such as breast, uterine, ovarian, prostate, and thyroid cancers. The objective of this study was to provide a comprehensive overview of previous studies investigating the relationship between endocrine-disrupting chemicals and the development of cancer.
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内分泌干扰物及其在癌症中的作用综述
内分泌干扰化学物质(EDCs)是一种环境普遍存在的化合物,具有与人体内分泌系统相互作用的能力,从而对人体健康产生有害影响。尽管公众健康一直受到关注,但内分泌干扰化学物质(EDCs)仍然是普通消费品的组成部分,对个人来说,它们是无处不在的污染物。鉴于许多流行病学和实验研究已经确立了干扰内分泌的化学品与对人类健康的不利影响之间的联系,人们越来越重视减少人类接触这些化合物。干扰内分泌的药物与对人类健康的不利影响以及对激素敏感的癌症(如乳腺癌、子宫癌、卵巢癌、前列腺癌和甲状腺癌)的易感性升高之间存在相关性。本研究的目的是对以往研究内分泌干扰物质与癌症发展之间关系的研究提供一个全面的概述。
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