One Size Does Not Fit All: The Need to Rethink the Metabolic Syndrome in Women

Maria Cristina Costa de Almeida, Marildes Luiza Castro, Larissa Espíndola, Luciana Nicolau Aranha, Thaís Salim, Gláucia Maria Moraes de Oliveira
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Abstract

Metabolic syndrome (MetS) is increasing at epidemic proportions worldwide. MetS and its components are frequent among Brazilian women (41.8%). Women are affected by changes in adipose tissue distribution, lipid profile, insulin resistance (IR), and vascular remodeling during their lives. These changes result from the lack of estrogen after menopause. There have been various attempts to propose a uniform origin for the clustering of the MetS components, including genetics, IR, obesity, lifestyle, sleep disturbances, inflammation, fetal and neonatal programming, and [...]
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一个尺寸不适合所有:需要重新思考女性代谢综合征
代谢综合征(MetS)在世界范围内呈流行趋势。MetS及其组成部分在巴西女性中很常见(41.8%)。女性在其一生中受到脂肪组织分布、脂质谱、胰岛素抵抗(IR)和血管重构变化的影响。这些变化是由于绝经后缺乏雌激素造成的。有各种各样的尝试提出一个统一的起源,为met组成的集群,包括遗传学,IR,肥胖,生活方式,睡眠障碍,炎症,胎儿和新生儿程序,和[…]
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0.00%
发文量
68
审稿时长
24 weeks
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