Havanensin-type Limonoids from the Stem Bark of Chisocheton pentandrus (Meliaceae)

IF 0.5 Q4 MULTIDISCIPLINARY SCIENCES Journal of Mathematical and Fundamental Sciences Pub Date : 2023-05-15 DOI:10.5614/j.math.fund.sci.2023.54.3.2
Dudi Runadi, Purnama Purnama, Supriatno Salam, Nulelasari Nurlelasari, Desi Harneti, Tri Mayanti, Rani Maharani, Unang Supratman, Yoshihito Shiono
{"title":"Havanensin-type Limonoids from the Stem Bark of Chisocheton pentandrus (Meliaceae)","authors":"Dudi Runadi, Purnama Purnama, Supriatno Salam, Nulelasari Nurlelasari, Desi Harneti, Tri Mayanti, Rani Maharani, Unang Supratman, Yoshihito Shiono","doi":"10.5614/j.math.fund.sci.2023.54.3.2","DOIUrl":null,"url":null,"abstract":"A new limonoid, belonging to the havanensin-type, called pentandricine E (1), alongside four other known types, i.e., trichilenone acetate (2), toonaciliatones C (3), 11α-acetoxyazadirone (4) and ceramicine I (5), were found in Chisocheton pentandrus stem bark. The structures of the isolated 1-5 were identified by NMR spectroscopy and HRTOFMS. Pentandricine E (1) displayed the highest cytotoxicity toward the MCF-7 breast cancer line with an IC50 value of 63.27 ± 0.21 mM.","PeriodicalId":16255,"journal":{"name":"Journal of Mathematical and Fundamental Sciences","volume":null,"pages":null},"PeriodicalIF":0.5000,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Mathematical and Fundamental Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5614/j.math.fund.sci.2023.54.3.2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
引用次数: 0

Abstract

A new limonoid, belonging to the havanensin-type, called pentandricine E (1), alongside four other known types, i.e., trichilenone acetate (2), toonaciliatones C (3), 11α-acetoxyazadirone (4) and ceramicine I (5), were found in Chisocheton pentandrus stem bark. The structures of the isolated 1-5 were identified by NMR spectroscopy and HRTOFMS. Pentandricine E (1) displayed the highest cytotoxicity toward the MCF-7 breast cancer line with an IC50 value of 63.27 ± 0.21 mM.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
五棱藤(Meliaceae)茎皮中的哈瓦那素型柠檬素
在Chisocheton pentandrus茎皮中发现了一种新的类柠檬素,称为pentandricine E(1),与其他四种已知类型,即醋酸三烯酮(2),toonaciliatones C (3), 11α-acetoxyazadirone(4)和ceramicine I(5)一起属于havanenin型。分离得到的1 ~ 5个化合物的结构通过NMR和HRTOFMS进行了鉴定。Pentandricine E(1)对MCF-7乳腺癌细胞系的细胞毒性最高,IC50值为63.27±0.21 mM。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
1.30
自引率
0.00%
发文量
0
审稿时长
24 weeks
期刊介绍: Journal of Mathematical and Fundamental Sciences welcomes full research articles in the area of Mathematics and Natural Sciences from the following subject areas: Astronomy, Chemistry, Earth Sciences (Geodesy, Geology, Geophysics, Oceanography, Meteorology), Life Sciences (Agriculture, Biochemistry, Biology, Health Sciences, Medical Sciences, Pharmacy), Mathematics, Physics, and Statistics. New submissions of mathematics articles starting in January 2020 are required to focus on applied mathematics with real relevance to the field of natural sciences. Authors are invited to submit articles that have not been published previously and are not under consideration elsewhere.
期刊最新文献
Simulation of Ultra-Short Laser Pulses Propagation and Ionization in Dual-Gas-Cells to Enhance the Quasi-Phase Matching of Harmonics Generation in Plasmas Structural and Photoluminescence Properties of Ca2+-Substituted Self-Activated Photoluminescence Material of Na2TiSiO5 Geochemistry of I-type Volcanic Arc Granitoid From Tanggamus Regency, Southern Sumatra Bioinformatic Analysis Strategy in Restriction Enzyme Selection for Indonesian Panulirus homarus Identification by PCR-RFLP Sedimentary Facies, Palynology, and Organic Geochemistry of Eocene Kalumpang Formation in Lariang and Karama Areas, West Sulawesi, Indonesia
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1