The Effect of Advanced Maternal Age on Adverse Outcomes Among Forceps-Assisted Vaginal Deliveries [ID: 1355950]

Elizabeth Cochrane, Angela Bianco, Chelsea DeBolt, Tahera Doctor, Sarah Roger, Kelly Wang
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Abstract

INTRODUCTION: Delivery rates among patients of advanced maternal age (AMA) are increasing. Prior studies have shown that AMA is associated with increased pregnancy risks and adverse outcomes. This study’s objective was to evaluate whether AMA is associated with an increase in obstetric anal sphincter injury (OASIS) rates among patients who undergo forceps-assisted vaginal deliveries (FAVDs). METHODS: This was an IRB-approved, retrospective cohort study of singleton gestations with FAVD at a single institution between 2017 and 2021. Primary outcome was rate of OASIS among patients with and without AMA. Secondary outcomes included quantitative blood loss (QBL), neonatal composite of subgaleal and cephalohematoma (adverse neonatal composite), and neonatal intensive care unit (NICU) admission. Quantitative blood loss was assessed using Mann-Whitney U test. Remaining outcomes were assessed using multivariate logistic regression models while adjusting for provider clustering and confounding patient characteristics including episiotomy and birth weight. RESULTS: Nine hundred eighty-three records were included, 704 non-AMA and 279 AMA. Patients of AMA were more likely to be Caucasian and were less likely to be Hispanic, nulliparous, experience spontaneous labor, and undergo episiotomy. Patients of AMA did not demonstrate increased odds of OASIS compared to non-AMA patients (odds ratio [OR] 1.21 [0.78, 1.89]). When age was assessed continuously, there was no association between increasing age and rates of OASIS (OR 1.02 [0.98, 1.06]). There was no statistically significant difference in QBL among the two groups (357.0 versus 350.0 cc, P =.20), NICU admission or adverse neonatal composite. CONCLUSION: Advanced maternal age does not appear to be a risk factor for OASIS or other adverse outcomes in patients undergoing FAVD.
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高龄产妇对产钳辅助阴道分娩不良结局的影响[j]
导读:高龄产妇(AMA)的分娩率正在上升。先前的研究表明,AMA与妊娠风险增加和不良后果有关。本研究的目的是评估AMA是否与产钳辅助阴道分娩(FAVDs)患者产科肛门括约肌损伤(OASIS)发生率的增加有关。方法:这是一项经irb批准的回顾性队列研究,研究对象是2017年至2021年在单一机构发生的单胎妊娠伴FAVD。主要结局是有或无AMA患者的OASIS发生率。次要结局包括定量失血量(QBL)、新生儿galeal下和头血肿复合(不良新生儿复合)和新生儿重症监护病房(NICU)入住情况。定量失血量采用Mann-Whitney U试验。在调整提供者聚类和混淆患者特征(包括外阴切开术和出生体重)的同时,使用多变量逻辑回归模型评估其余结果。结果:共纳入983例,其中非AMA 704例,AMA 279例。AMA患者多为白种人,西班牙裔、无产、自然分娩和会阴切开术患者较少。与非AMA患者相比,AMA患者的OASIS发生率没有增加(比值比[OR] 1.21[0.78, 1.89])。当持续评估年龄时,年龄的增加与OASIS发生率之间没有关联(OR为1.02[0.98,1.06])。两组间QBL (357.0 vs 350.0 cc, P = 0.20)、新生儿重症监护病房入院或新生儿不良综合情况均无统计学差异。结论:高龄产妇似乎不是FAVD患者发生OASIS或其他不良结局的危险因素。
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