Antifungal Susceptibility Pattern of Malassezia sp. Isolated from the North-East Region of India

Q4 Biochemistry, Genetics and Molecular Biology Acta Microbiologica Bulgarica Pub Date : 2023-06-01 DOI:10.59393/amb23390213
E.K. Marak, Th.N. Singh, Kh.S. Devi, Y.R.B. Singh, Kh.R. Devi
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Abstract

Malassezia comprises lipophilic yeasts which are considered as commensals of the skin and become pathogenic under certain conditions. One hundred and forty-four specimens from clinically suspected cas¬es of pityriasis versicolor were collected and processed microbiologically. Malassezia sp. was identified phenotypically and MIC for common antifungal drugs was performed. Thirty-three percent of the collected specimens were culture positive for Malassezia sp. M. furfur (50%) is the commonest species isolated from pityriasis versicolor cases, followed by M. globosa (35.4%). The study observed low MICs for itraconazole and voriconazole. Itraconazole is the choice of drug for the treatment of Malassezia infection.
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印度东北地区马拉色菌抗真菌药敏型分析
马拉色菌包括亲脂酵母菌,被认为是皮肤的共栖物,在某些条件下具有致病性。对144例临床疑似花斑糠疹标本进行微生物学处理。对马拉色菌进行表型鉴定,并对常用抗真菌药物进行MIC检测。33%的采集标本对马拉色菌培养呈阳性。从花斑糠疹病例中分离到的马拉色菌最常见的是毛霉(50%),其次是globosa(35.4%)。研究发现伊曲康唑和伏立康唑的mic较低。伊曲康唑是治疗马拉色菌感染的首选药物。
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来源期刊
Acta Microbiologica Bulgarica
Acta Microbiologica Bulgarica Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)
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0.40
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0
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