The long-term outcomes of the Anderson-Kestenbaum procedure

Jeffrey Kuziel, Hannah Pope, Aishwarya J. Kothapalli, Scott A. Larson, Arlene Drack, Alina V. Dumitrescu
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Abstract

Introduction Nystagmus is an involuntary, conjugated, rhythmic movement of the eye that can be idiopathic or secondary to ocular or neurologic pathologies. Patients with nystagmus often have a position of gaze in which their symptoms are dampened or absent, referred to as the “null zone.” The Anderson-Kestenbaum procedure is a bilateral recess-resect procedure of the four horizontal rectus muscles which aims to bring the null position into the primary gaze. This study aims to further elucidate long-term outcomes and factors associated with optimal postoperative outcomes. Methods Patients with a diagnosis of nystagmus and a surgical code for strabismus between June 1990 and August 2017 were considered for inclusion in the study. Patients were included if they had undergone the Anderson-Kestenbaum procedure and had follow-up lasting at least 24 months post-operatively. Data collected included demographic information, characteristics of the nystagmus, underlying etiology of nystagmus, and pre-and post-operative measurements. Results 25 patients were included. At their last recorded follow-up, 44% of patients achieved an optimal surgical outcome -an abnormal head position of 10 degrees or less. 88% of patients showed an overall improvement in their head posture at the last follow-up. The absence of an abnormal head position at the visit closest to 24 months post-operatively was found to be significantly associated with the lack of a significant head position at the last follow-up visit. Optimal surgical outcomes were not significantly associated with the underlying diagnosis, the direction of the abnormal head position, or the type of nystagmus. Discussion The relatively long follow-up of this cohort allows this study to further elucidate the long-term outcomes of the Anderson-Kestenbaum procedure. Overall, our results suggest that although improvement in head position post-operatively is likely, it is still expected that many patients will have a residual abnormal head position after the procedure. The results of this study are helpful in counseling patients, especially knowing that if they do not have a significant head position at 24 months follow-up, they are unlikely to develop one. However, due to the small sample size, larger cohorts and more standardized follow-up may provide further insight into the procedure’s outcomes.
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安德森-凯斯滕鲍姆手术的长期效果
眼球震颤是一种不自主的、共轭的、有节奏的眼球运动,可以是特发性的,也可以是继发于眼部或神经系统疾病的。眼球震颤患者通常有一个凝视的位置,在这个位置上,他们的症状被抑制或消失,被称为“空区”。Anderson-Kestenbaum手术是一种双侧四个水平直肌的凹陷切除手术,目的是使零位进入主要凝视。本研究旨在进一步阐明远期预后和与最佳术后预后相关的因素。方法将1990年6月至2017年8月期间诊断为眼球震颤并有斜视手术码的患者纳入研究。如果患者接受了安德森-凯斯滕鲍姆手术并术后随访至少24个月,则纳入患者。收集的数据包括人口统计学信息、眼球震颤的特征、眼球震颤的潜在病因以及术前和术后的测量。结果共纳入25例患者。在他们最后一次记录的随访中,44%的患者获得了最佳的手术结果-头部位置异常10度或更小。88%的患者在最后一次随访中头部姿势有了整体改善。术后近24个月就诊时头部位置不异常与最后一次随访时头部位置不明显显著相关。最佳手术结果与潜在的诊断、异常头部位置的方向或眼球震颤的类型没有显著相关性。该队列相对较长的随访使本研究能够进一步阐明Anderson-Kestenbaum手术的长期结果。总的来说,我们的结果表明,尽管术后头部位置有可能得到改善,但仍有许多患者在术后仍会有残留的异常头部位置。本研究的结果有助于为患者提供咨询,特别是知道如果他们在24个月的随访中没有明显的头部位置,他们就不太可能发展成一个。然而,由于样本量小,更大的队列和更标准化的随访可能提供对手术结果的进一步了解。
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