Mature Teratoma of The Lung : A Case Report

Priangga Adi Wiratama, Alphania Rahniayu, Vira Yasmina Ramadhani
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Abstract

Background: Mature teratoma is a germinal cell tumor that is commonly found in ovaries and testis. Mature teratoma in the lung region is a rare case. According to the literature there are only 67 cases worldwide starting from 1939 to 2007. There were one cases in Dr. Soetomo general hospital during January 2013 – December 2017.Objective: Mature teratoma in the lung region is a rare case. Presenting in a case report would be beneficial for pathology databaseCase Presentation: A 19 years old man came to hospital with shortness of breath within 3 months ago. It was followed with hemoptysis, trichoptysis and coughing out tooth. CT Scan examination showed an irregular walled cavity with semisolid component and calcification along with a description of "air cresent sign". In thoracotomy tumor excision obtained multilobulated mass size 8.5x6,8x5,6 cm, yellowish-gray white color, and firm consistency. There were also hair and tooth components. The microscopic representation shows pieces of lung tissue with tumor growth coated with squamous epithel with a stroma containing adnexal skin glands, fatty tissue, cartilage tissue, and serous glands (asinar). Discussion: Mature teratoma of the lung is one of the rare tumors, with symptoms of chest pain, hemoptysis, and trichoptysis. Mature teratoma of the lung is generally cystic and multiloculated, but can also be solid, encapsulated. On microscopic examination, shows a picture of various components of ectoderm, mesoderm and endoderm.Conclusion: Mature teratoma of the lung is a rare tumor. Diagnosis was based from clinical findings, radiologic examination, and confirmed with histopathology and immunohistochemistry.
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肺成熟畸胎瘤1例报告
背景:成熟畸胎瘤是一种常见于卵巢和睾丸的生发细胞肿瘤。成熟畸胎瘤在肺区域是一个罕见的病例。根据文献,从1939年到2007年,全世界只有67例。2013年1月至2017年12月期间,Soetomo博士综合医院有1例病例。目的:肺区成熟畸胎瘤是一种罕见的病例。病例报告将有助于病理数据库的建立。病例报告:一名19岁男性,3个月前因呼吸急促入院。随后出现咯血、滴血、咳牙。CT检查显示不规则壁腔,半固体成分,钙化,并描述为“气新月征”。在开胸切除肿瘤时,得到8.5x6、8x5、6 cm的多分叶状肿块,颜色黄灰白色,致密。还有头发和牙齿的成分。显微镜下显示肿瘤生长的肺组织片被鳞状上皮覆盖,间质包含附件皮腺、脂肪组织、软骨组织和浆液腺(腺)。讨论:肺成熟畸胎瘤是一种罕见的肿瘤,其症状为胸痛、咯血、三趾。成熟的肺畸胎瘤通常是囊性的和多室的,但也可以是实心的,被包裹的。镜检显示外胚层、中胚层和内胚层的不同组成部分。结论:肺成熟畸胎瘤是一种罕见的肿瘤。诊断依据临床表现、放射学检查、组织病理学和免疫组织化学证实。
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