{"title":"Synthesis of Crop Protection Agent Mandipropamid","authors":"","doi":"10.56042/ijc.v62i9.3120","DOIUrl":null,"url":null,"abstract":"A simple synthesis of a novel fungicide Mandipropamid has been achieved in 6 steps, with an overall yield 43%. Synthesis started from commercially available starting materials, 4-chloroacetophenone and vanillin. The key steps involved in the synthesis are Cannizzaro and Henry reactions, amide bond formation and O-propargylation.","PeriodicalId":29765,"journal":{"name":"INDIAN JOURNAL OF CHEMISTRY","volume":"44 1","pages":"0"},"PeriodicalIF":0.4000,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"INDIAN JOURNAL OF CHEMISTRY","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.56042/ijc.v62i9.3120","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
A simple synthesis of a novel fungicide Mandipropamid has been achieved in 6 steps, with an overall yield 43%. Synthesis started from commercially available starting materials, 4-chloroacetophenone and vanillin. The key steps involved in the synthesis are Cannizzaro and Henry reactions, amide bond formation and O-propargylation.