Clinical characteristics of sudden hearing loss during pregnancy

Xiao‐Nan Wu, Hong‐Yang Wang, Xiao‐Long Zhang, Guo‐Hui Chen, Jing Guan, Yun Gao, Da‐Yong Wang, Qiu‐Ju Wang
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Abstract

Abstract Objective The objective of this study was to explore the clinical characteristics and management of sudden hearing loss (HL) during pregnancy, thus better guiding the clinical practice. Methods The clinical and follow‐up data of 17 patients (17 ears) with sudden HL during pregnancy were analyzed retrospectively (the observe group). Twelve nonpregnant female patients (12 ears) with sudden HL of similar clinical characteristics were selected as the control group. The prognosis of the two groups was compared. All the patients were followed up after delivery, and two of them were readmitted to the hospital 1–2 months after delivery. Results The observe group had better improvement in hearing and a higher response rate compared to the control group. The pure tone hearing and speech recognition rate of patients could still be improved after the readmitted treatment, and the hearing could partially recover spontaneously during follow‐up. The laboratory indicators that affect the inflammatory response and coagulation pathway were significantly different between the two groups. Conclusions The hearing condition of sudden HL during pregnancy is severe, and the prognosis of these patients is better than nonpregnant patients of similar clinical characteristics. Postpartum treatment is still effective, and some patients showed self‐healing with time during follow‐up. The inflammatory response and coagulation function may affect the hearing of patients through a metabolic pathway.
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妊娠期突发性听力损失的临床特点
摘要目的探讨妊娠期突发性听力损失(HL)的临床特点及处理方法,更好地指导临床实践。方法回顾性分析17例(17耳)妊娠期突发性HL患者的临床及随访资料(观察组)。选择临床特征相似的突发性HL女性患者12例(12耳)作为对照组。比较两组患者的预后。所有患者均在分娩后随访,其中2例于分娩后1 ~ 2个月再次入院。结果观察组患者听力改善明显,有效率高于对照组。再次入院治疗后,患者的纯音听力和语音识别率仍可得到改善,随访时听力可部分自发恢复。两组间影响炎症反应及凝血途径的实验室指标差异有统计学意义。结论突发性HL妊娠期听力状况严重,预后优于临床特征相似的非妊娠期患者。产后治疗仍然有效,随著时间的推移,部分患者表现出自愈。炎症反应和凝血功能可能通过代谢途径影响患者的听力。
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CiteScore
4.10
自引率
0.00%
发文量
283
审稿时长
13 weeks
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