Disseminated intravascular coagulation in a pregnant woman with coronavirus disease 2019 infection: A case report

Anita Krsman, Marija Kupresanin, Branislava Baturan, Sanja Bulatovic, Djordje Petrovic, Djordje Ilic
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Abstract

Introduction. Coronavirus infection may cause numerous complications in pregnant women, as well as an increased risk for the fetus. Disseminated intravascular coagulation and other coagulopathies can be caused by coronavirus disease 2019 infection. Case Report. A 22-year-old primigravida presented with a nineday history of dry cough, myalgia, nausea and fever. A nasopharyngeal swab for severe acute respiratory syndrome coronavirus 2 infection was positive. The patient?s condition rapidly deteriorated, resulting in severe liver damage and disseminated intravascular coagulation. Fetal cardiotocography showed a silent curve with late decelerations, while the umbilical artery Doppler showed end-diastolic block, indicating a fetal distress. Emergency cesarean section was performed at 28+5 weeks of gestation. After the cesarean section, the patient was treated with blood derivatives, thromboprophylaxis and supportive therapy and recovered quickly. Unfortunately, the premature infant died three hours after birth. Conclusion. It is very important to simultaneously monitor the parameters of the mother?s coagulation system, as well as the condition of the fetus, because there is a possibility of developing coagulopathies, including disseminated intravascular coagulation.
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2019冠状病毒病感染孕妇弥散性血管内凝血1例
介绍。冠状病毒感染可能会导致孕妇出现许多并发症,并增加胎儿的风险。播散性血管内凝血和其他凝血疾病可由2019冠状病毒感染引起。病例报告。22岁初产妇,有9天干咳、肌痛、恶心和发热病史。严重急性呼吸综合征冠状病毒2型感染鼻咽拭子阳性。病人吗?S病情迅速恶化,导致严重的肝损害和弥散性血管内凝血。胎儿心脏造影显示无音曲线伴迟发性减速,脐动脉多普勒显示舒张末期阻滞,提示胎儿窘迫。妊娠28+5周行急诊剖宫产。剖宫产术后给予血液衍生物、血栓预防及支持性治疗,恢复迅速。不幸的是,这名早产儿在出生三小时后死亡。结论。同时监测母亲的参数是非常重要的。因为有可能发生凝血病,包括弥散性血管内凝血。
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