Cancer chemoprevention and healthy lifestyle

Olivia R Gennaro, Adam D Burke, Ronald J Fecek, Daniel M Borsch, Amitabha Ray
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Abstract

A growing body of evidence suggests that chronic low-grade inflammation and oxidative stress may lead to cancer development. These discoveries complement the usual focus of cancer prevention that primarily concentrates on carcinomas, i.e., ectodermal or endodermal (embryonic) tissue-derived cancers, which are more exposed to lifestyle/environment-related risk factors. Based on these findings, cancer preventive strategies can be formulated by using a number of dietary phytochemicals that display inhibitory effects on oxidative stress, inflammation, and other tumor-linked phenomena such as angiogenesis, cell proliferation, and DNA damage. Overall, a positive lifestyle and healthy food habits can reduce cancer risk.
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癌症化学预防和健康的生活方式
越来越多的证据表明,慢性轻度炎症和氧化应激可能导致癌症的发展。这些发现补充了癌症预防的通常重点,主要集中在癌症,即外胚层或内胚层(胚胎)组织衍生的癌症,这些癌症更容易受到生活方式/环境相关风险因素的影响。基于这些发现,癌症预防策略可以通过使用一些膳食植物化学物质来制定,这些植物化学物质对氧化应激、炎症和其他与肿瘤相关的现象(如血管生成、细胞增殖和DNA损伤)具有抑制作用。总的来说,积极的生活方式和健康的饮食习惯可以降低患癌症的风险。
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