Prognostic Significance of Tumor-infiltrating Lymphocytes and Anti-programmed Death-ligand 1 Therapy in Sinonasal Mucosal Melanoma: A 10-year Experience at a Single Institution

Jana Tarabay, Dong Ren, Ibe Ifegu, Sherehan Zada, Robert Edwards, Jefferson Chan, Edward C. Kuan, Beverly Wang
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Abstract

Background and objectivesSinonasal mucosal melanoma (SNMM) is a rare aggressive malignancy that presents with dismal outcomes and a high metastatic propensity. The prognostic factors as well as therapeutic regimens remain largely unknown due to the rarity of SNMM. This study aimed to assess the characteristics of SNMM patients associated with a better prognosis.
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肿瘤浸润淋巴细胞和抗程序性死亡配体1治疗在鼻黏膜黑色素瘤中的预后意义:一个机构的10年经验
背景与目的鼻黏膜黑色素瘤(SNMM)是一种罕见的侵袭性恶性肿瘤,预后不佳且具有高转移倾向。由于SNMM的罕见性,其预后因素以及治疗方案在很大程度上仍然未知。本研究旨在评估SNMM患者与较好预后相关的特征。
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