Quantifying the Prevalence of Acute Vestibular Neuritis through Big Data Analysis

Chul Young Yoon, Seulgi Hong, Ji-Yun Park, Young Joon Seo
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Abstract

Objectives: Big data analytics in healthcare research have gained momentum, offering unprecedented opportunities to investigate complex medical conditions like acute vestibular neuritis (AVN). However, an inappropriate definition can introduce bias and inaccuracies into prevalence estimation, making the results unreliable and hindering cross-study comparisons. The Health Insurance data in South Korea will be used to create a robust operational definition for AVN.Methods: The study utilized the National Patients Sample dataset from the Health Insurance Review and Assessment Service (HIRA) of the Republic of Korea. The operational definition of AVN was defined using the HIRA data, which includes specific codes for diagnosis, testing, and medications. The revised categorization scheme for AVN was presented as case 1 through case 5, with criteria for each category.Results: The optimal conditions are deemed to be those that encompass the outcomes of both case 5 and case 1-1, encompassing all conditions. The study also provided prevalence estimates for subgroups based on demographic factors (age, sex), and found a consistent pattern throughout all years, sex, and age.Conclusions: The study analyzed the prevalence of AVN in case 1 and case 5, which were similar to the reference prevalence of 3.5 per 100,000 people reported in other countries. The study’s results are encouraging for several reasons, including the validity of the operational definitions used, and the agreement between the study’s prevalence estimates and the reference prevalence. The operational definition in statistics, in the context of big data, serves as a precise and standardized criterion.
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通过大数据分析量化急性前庭神经炎的患病率
目的:医疗保健研究中的大数据分析获得了动力,为调查复杂的医疗状况(如急性前庭神经炎(AVN))提供了前所未有的机会。然而,不恰当的定义可能会在患病率估计中引入偏差和不准确性,使结果不可靠并阻碍交叉研究比较。韩国的健康保险数据将用于创建AVN的稳健操作定义。方法:本研究利用韩国健康保险审查和评估服务(HIRA)的国家患者样本数据集。AVN的操作定义是使用HIRA数据定义的,其中包括诊断、测试和药物的特定代码。AVN的修订分类方案按案例1至案例5提出,每个类别都有标准。结果:最优条件被认为是包括案例5和案例1-1的结果,包括所有条件。该研究还提供了基于人口统计学因素(年龄、性别)的亚组患病率估计,并发现了贯穿所有年份、性别和年龄的一致模式。结论:本研究分析了病例1和病例5的AVN患病率,与其他国家报告的参考患病率(每10万人3.5例)相似。这项研究的结果令人鼓舞,原因有几个,包括所使用的业务定义的有效性,以及研究的流行率估计数与参考流行率之间的一致性。统计学中的操作性定义,在大数据背景下,是一个精确、规范的标准。
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