Physical Stability, Photostability, and Sunscreen Effectiveness of Combination Cream of Arabica Green Coffee Bean Extract (Coffea arabica) and Octyl Methoxycinnamate

Nanda Tsalasani Zulfaidah, Endang Lukitaningsih, Abdul Karim Zulkarnain
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Abstract

Arabica green coffee beans (AGCB) have antioxidant compounds as photo protectors. It’s used to stabilize and increase the SPF value of octyl methoxycinnamate in sunscreen because its effectiveness will be decreased when exposed to UV light. The purpose of this study was to determine the effect of a combination of various concentrations of arabica green coffee bean (AGCB) extract and octyl methoxycinnamate (OMC) on the physical properties and SPF value of sunscreen cream. AGCB extract with concentrations (F1) 0%; (F2) 2.5%; (F3) 5%; (F4) 7.5% (with the addition of OMC concentration of 7.5%), and (F5) 7.5% (without the addition of OMC). The formulas were tested for physical properties to determine stability in 4 weeks of storage, cycling test for 4 cycles, and photostability to determine the SPF value and irritation test on the best formula. The results of the physical stability test on the five formulas showed a sig value > 0.05 which means the preparation is stable. Formulas F1, F2, F3, F4, and F5 with exposure of 1 hour, 5 hours, and 10 hours obtained a significance value > 0.05, which means that the presence of UV light exposure in the AGCB extract combination cream can stabilize the decrease in SPF value. Formula 4, which is stable without separation during the cycling test and the stability of the SPF value of 41, then in the irritation test does not cause irritation so it can be concluded that formula 4 is the optimum formula.
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阿拉比卡绿咖啡豆提取物(阿拉比卡咖啡)和甲氧基肉桂酸辛酯组合霜的物理稳定性、光稳定性和防晒效果
阿拉比卡绿咖啡豆(AGCB)含有抗氧化化合物作为光保护剂。用于稳定和增加甲氧基肉桂酸辛酯在防晒霜中的SPF值,因为它在紫外线照射下会降低防晒效果。本研究的目的是确定不同浓度的阿拉比卡绿咖啡豆(AGCB)提取物和甲氧基肉桂酸辛酯(OMC)的组合对防晒霜的物理性能和SPF值的影响。AGCB提取物,浓度为(F1) 0%;(F2) 2.5%;(F3) 5%;(F4) 7.5%(添加了浓度为7.5%的OMC), (F5) 7.5%(未添加OMC)。对配方进行了物理性能测试,以确定4周的储存稳定性,4周的循环测试,光稳定性测试,以确定最佳配方的SPF值和刺激性测试。五种配方的物理稳定性试验结果均为sig值>0.05表示制剂是稳定的。公式F1、F2、F3、F4、F5在暴露时间为1小时、5小时、10小时时具有显著性值>0.05,这意味着AGCB提取物组合霜中存在紫外线照射可以稳定SPF值的下降。由于配方4在循环试验中稳定不分离,且SPF值稳定在41,因此在刺激试验中不引起刺激,因此可以得出配方4为最佳配方。
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CiteScore
0.60
自引率
0.00%
发文量
10
审稿时长
15 weeks
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