René Ghislain Essomba, Rostand Munkam Mbe, Marie Paule Ngongang, Claire Bitchong Ekono, Valentina Josiane Ngo, Nassif Seni, Philippe Salomon Nguwoh, Pulchérie Thérèse Ateba, Severin Donald Kamdem, Justin Komguep Nono, Myriam Sylvie Ambomo, Marie Claire Okomo, François Xavier Mbopi-Kéou
{"title":"Plasma IL-33 levels and immune activation in HIV-TB coinfection: a cross-sectional study in Yaoundé, Cameroon","authors":"René Ghislain Essomba, Rostand Munkam Mbe, Marie Paule Ngongang, Claire Bitchong Ekono, Valentina Josiane Ngo, Nassif Seni, Philippe Salomon Nguwoh, Pulchérie Thérèse Ateba, Severin Donald Kamdem, Justin Komguep Nono, Myriam Sylvie Ambomo, Marie Claire Okomo, François Xavier Mbopi-Kéou","doi":"10.11604/pamj.2023.46.13.41152","DOIUrl":null,"url":null,"abstract":"Introduction: HIV-1 and Mtb are characterized by immune activation and unbalances production of cytokines, but the expression of IL33 in HIV/TB coinfection remain understudied. This study aimed to evaluate the level of IL-33 in plasma of HIV and M.tuberculosis (HIV/TB) coinfected patients compared to patients with respective mono infections in Yaoundé.","PeriodicalId":131455,"journal":{"name":"The Pan African Medical Journal","volume":"14 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Pan African Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11604/pamj.2023.46.13.41152","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: HIV-1 and Mtb are characterized by immune activation and unbalances production of cytokines, but the expression of IL33 in HIV/TB coinfection remain understudied. This study aimed to evaluate the level of IL-33 in plasma of HIV and M.tuberculosis (HIV/TB) coinfected patients compared to patients with respective mono infections in Yaoundé.