Fabrication of biomimetic antibacterial titanium surfaces by hydrothermal oxidation

Patrick Doll, Lea Kremer, Ralf Ahrens, Litsy Hüschelrath
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引用次数: 0

Abstract

Abstract Within this paper we demonstrate a novel approach to create antibacterial nanostructures on the implant material titanium grade 23 by a high-pressure oxidation method. Titanium samples were oxidized and resulting nanostructures were characterized using scanning electron microscopy and contact angle measurements. Antibacterial properties were tested using Escherichia coli and Bacillus subtilis as common lab strains. In addition, cytotoxicity was determined according to ISO 10993-5 standards. Results reveal that the fabricated nanostructures have similar antibacterial properties known from different insect wings like dragonflies or cicadas and have no cytotoxic effect.
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水热氧化法制备仿生抗菌钛表面
摘要在本文中,我们展示了一种利用高压氧化法在植入材料钛级23上制备抗菌纳米结构的新方法。利用扫描电镜和接触角测量对钛样品进行氧化和纳米结构表征。以大肠杆菌和枯草芽孢杆菌为常用实验菌株,对其抑菌性能进行了测试。此外,根据ISO 10993-5标准测定细胞毒性。结果表明,制备的纳米结构具有与蜻蜓或蝉等不同昆虫翅膀相似的抗菌性能,且无细胞毒性作用。
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来源期刊
Current Directions in Biomedical Engineering
Current Directions in Biomedical Engineering Engineering-Biomedical Engineering
CiteScore
0.90
自引率
0.00%
发文量
239
审稿时长
14 weeks
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