Prevalence of Hepatitis C Virus Infection among Chronic Kidney Disease Patients on Regular Hemodialysis

Noor Mohammad, Rahmat Karim, Muhammad Waqas Khan, Muhammad Ayaz, Aamir Nabi, None Khursheed
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Abstract

OBJECTIVES To determine the frequency of the Hepatitis C Virus in patients with chronic kidney disease receiving regular hemodialysis. METHODOLOGY At a tertiary care hospital in Peshawar, 211 patients were observed to ascertain the frequency of the Hepatitis C Virus in chronic kidney disease patients receiving regular hemodialysis. The technique of non-probability sequential sampling was employed to acquire samples. SPSS version 26.0 was used. RESULTSAmong the CKD patients with Hepatitis C Virus (HCV) infection, a higher proportion of males (48.5%) tested positive compared to females (28.1%). Furthermore, the prevalence of HCV infection was significantly higher in CKD patients residing in urban areas (98.5%) compared to those in rural areas (1.5%). The statistical analysis indicated a significant association between the prevalence of Hepatitis and the factors of gender and residency (P value = 0.002). Out of 211, hepatitis C-positive patients 66.2% were diabetics and hypertensive were 77.9%. CONCLUSION Hospitalized CKD patients have a considerably higher frequency of hepatitis C infection. To stop the spread of the hepatitis C virus, nephrology wards should undertake strict universal infection control procedures.
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慢性肾脏疾病定期血液透析患者丙型肝炎病毒感染的流行病学研究
目的了解定期接受血液透析的慢性肾病患者中丙型肝炎病毒的感染频率。在白沙瓦的一家三级保健医院,对211名患者进行了观察,以确定定期接受血液透析的慢性肾病患者中丙型肝炎病毒的频率。采用非概率序贯抽样技术获取样本。采用SPSS 26.0版本。结果CKD合并丙型肝炎病毒(HCV)感染的患者中,男性(48.5%)阳性比例高于女性(28.1%)。此外,居住在城市地区的CKD患者的HCV感染率(98.5%)明显高于居住在农村地区的患者(1.5%)。统计分析显示肝炎患病率与性别、居住地等因素有显著相关性(P值= 0.002)。在211例丙型肝炎阳性患者中,糖尿病患者占66.2%,高血压患者占77.9%。结论住院CKD患者丙型肝炎感染发生率较高。为了阻止丙型肝炎病毒的传播,肾内科病房应执行严格的普遍感染控制程序。
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