Transarterial embolization for delayed bleeding after percutaneous nephrolithotomy

Fatma Gonca Eldem, Ferdi Çay, Ahmet Güdeloğlu, Bora Peynircioğlu
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Abstract

Objectives: The study aimed to evaluate the effectiveness and reliability of transarterial embolization (TAE) in managing delayed bleeding after percutaneous nephrolithotomy (PNL). Materials and Methods: Patients presenting to our hospital’s emergency department with hematuria following PNL and treated with TAE were included in the retrospective analysis. Demographic, clinical, and radiological data were collected. Technical and clinical success rates of TAE were calculated. The impact of the embolization procedure on kidney function was determined using angiographic images, and pre- and post-procedure serum creatinine levels. Results: A total of 13 patients included in the study presented with intermittent visible hematuria. The average interval between hematuria onset and PNL was 11.92±7.27 days. No hemodynamic instability was observed in any patient. CT angiography identified vascular pathology in 11 patients (84.6%), who subsequently underwent renal angiography for TAE without conservative treatment. Pseudoaneurysms were found in 7 patients (63.6%), and both pseudoaneurysms and arteriovenous fistulae in 4 patients (36.4%). Technical success was achieved in all embolization procedures. Hematuria resolved in all patients during follow up with a clinical success rate of 100%. Renal parenchymal loss after embolization was <%10 in 8 patients (72.7%), %11-24 in 2 patients (18.2%), and %25-50 in 1 patient (7.7%). There was no significant difference in serum creatinine levels before (mean 1.09±0.53 mg/dl) and after (mean 1.06±0.71 mg/dl) TAE (p=0.5). No major procedure related complications were observed. Conclusions: TAE is an effective and safe method for the treatment of delayed bleeding following PNL. CT angiography facilitates diagnosis and treatment planning for patients with hematuria after discharge. Early TAE for patients with identified vascular pathology can increase technical and clinical success rates.
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经皮肾镜取石术后迟发性出血经动脉栓塞治疗
目的:本研究旨在评估经动脉栓塞(TAE)治疗经皮肾镜取石术(PNL)后迟发性出血的有效性和可靠性。材料与方法:回顾性分析在我院急诊科就诊的PNL术后血尿并经TAE治疗的患者。收集了人口学、临床和放射学数据。计算TAE的技术成功率和临床成功率。栓塞手术对肾功能的影响是通过血管造影图像和手术前后血清肌酐水平来确定的。结果:研究中共有13例患者出现间歇性可见血尿。血尿发作至PNL的平均间隔时间为11.92±7.27天。所有患者均未见血流动力学不稳定。CT血管造影发现血管病变11例(84.6%),随后行肾血管造影治疗TAE,未进行保守治疗。假性动脉瘤7例(63.6%),假性动脉瘤合并动静脉瘘4例(36.4%)。栓塞术均取得技术上的成功。所有患者在随访期间血尿均得到解决,临床成功率为100%。栓塞后肾实质损失8例(72.7%)%10,2例(18.2%)%11-24,1例(7.7%)%25-50。TAE前(平均1.09±0.53 mg/dl)与TAE后(平均1.06±0.71 mg/dl)血清肌酐水平差异无统计学意义(p=0.5)。未观察到重大手术相关并发症。结论:TAE是一种安全有效的治疗PNL后迟发性出血的方法。CT血管造影有助于患者出院后血尿的诊断和治疗计划。对血管病变患者进行早期TAE可以提高技术和临床成功率。
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