Plasma Cell Neoplasms with Unusual Anatomic Locations, Morphology, Phenotype, and Review of Literature: A Case Series

Abstract

Background and objectivesPlasma cell neoplasms are well-known for having diverse morphological and phenotype presentations and less commonly unusual immunophenotypical profiles. Such unexpected immunophenotypical variability could lead to inaccurate impressions upon initial assessment, thus delaying an accurate diagnosis. Here, the authors report seven plasma cell neoplasm cases with unusual morphology, immunophenotype, or unusual anatomic locations from the archives of Montefiore Medical Center Hematopathology department to highlight key considerations involved in diagnosing plasma cell neoplasms.