Point prevalence multicenter survey of antimicrobial consumption in Russian hospitals: results of the Global-PPS 2021

Yu.А. Belkova, S.А. Rachina, R.S. Kozlov, V.G. Kuleshov, I.S. Vasilieva, A.A Kurkova, Е.N. Bochanova, Е.V. Elokhina, D.А. Popov, U.S. Portnyagina, О.V. Reshetko, Igor N. Sychev, V.D. Shegimova, D.V. Drogashevskaya, M.S. Chesnokova, E.V. Dovgan, S.O. Korolkov, E.M. Kurtz, A.I. Levitan, T.S. Lutsevich, R.A. Osokina, L.D. Popova, E.E. Sventitskaya, L.V. Fedina
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Abstract

Objective. To evaluate prescribing patterns of antimicrobials and quantify them in relation to quality indicators in Russian multi-field hospitals. Materials and Methods. Point Prevalence Survey of Antimicrobial Consumption as a part of an international Global-PPS project was conducted in 8 multi-field hospitals in different Russian cities (Krasnoyarsk, Moscow, Omsk, Saratov, Smolensk, Ulan-Ude, Yakutsk) during the period from May till December 2021. Case records of patients who received therapeutic or prophylactic systemic antimicrobial agents were analyzed. Local practices of antimicrobials’ utilization were evaluated in relation to quality indicators defined by the study protocol. Results. Common mistakes requiring a prompt intervention included low adherence to clinical guidelines, absence of stop/review dates in the medical records, extended duration of surgical prophylaxis, III generation cephalosporin’s overuse and low rate of targeted therapy. Conclusions. The results of the project can be valuable for the improvement to antimicrobial utilization approaches at the study centers as well as for monitoring of antimicrobial stewardship programs’ implementation.
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俄罗斯医院抗菌药物消费的点流行多中心调查:Global-PPS 2021的结果
目标。评估抗微生物药物的处方模式,并将其与俄罗斯多野战医院的质量指标进行量化。材料与方法。作为国际全球pps项目的一部分,于2021年5月至12月期间在俄罗斯不同城市(克拉斯诺亚尔斯克、莫斯科、鄂木斯克、萨拉托夫、斯摩棱斯克、乌兰乌德、雅库茨克)的8家多野战医院进行了抗微生物药物消费点流行调查。对接受治疗性或预防性全身性抗菌药物治疗的患者病例记录进行分析。根据研究方案定义的质量指标对抗菌素使用的地方做法进行了评估。结果。需要及时干预的常见错误包括不遵守临床指南、医疗记录中没有停止/审查日期、手术预防持续时间延长、第三代头孢菌素过度使用和靶向治疗率低。结论。该项目的结果对于研究中心的抗菌素利用方法的改进以及对抗菌素管理计划实施的监测具有重要价值。
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