Ana Paula Vilela, Leandro Ferreira, Patrícia Bubna Biscaia, Karine Letícia da Silva, Flávio Luís Beltrame, Guilherme dos Anjos Camargo, Marcia Rezende, Jessica Mendes Nadal, Andressa Novatski, Jane Manfron, Alessandro Dourado Loguercio, Paulo Vitor Farago
{"title":"Preparation, Characterization and Stability Study of Eugenol-Loaded Eudragit RS100 Nanocapsules for Dental Sensitivity Reduction","authors":"Ana Paula Vilela, Leandro Ferreira, Patrícia Bubna Biscaia, Karine Letícia da Silva, Flávio Luís Beltrame, Guilherme dos Anjos Camargo, Marcia Rezende, Jessica Mendes Nadal, Andressa Novatski, Jane Manfron, Alessandro Dourado Loguercio, Paulo Vitor Farago","doi":"10.1590/1678-4324-ssbfar-2023230300","DOIUrl":null,"url":null,"abstract":"HIGHLIGHTS Eugenol-loaded Eudragit RS100 nanocapsules were suitably obtained and characterized. A simple and fast UPLC/MS-MS method for determining eugenol in Eudragit RS100 nanocapsules was developed and validated. Eugenol-loaded Eudragit RS100 nanocapsules showed physical stability after 60 days of preparation. Eugenol-loaded Eudragit RS100 nanocapsules may be further used for reducing dental sensitivity.","PeriodicalId":9169,"journal":{"name":"Brazilian Archives of Biology and Technology","volume":"40 1","pages":"0"},"PeriodicalIF":1.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brazilian Archives of Biology and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1590/1678-4324-ssbfar-2023230300","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
HIGHLIGHTS Eugenol-loaded Eudragit RS100 nanocapsules were suitably obtained and characterized. A simple and fast UPLC/MS-MS method for determining eugenol in Eudragit RS100 nanocapsules was developed and validated. Eugenol-loaded Eudragit RS100 nanocapsules showed physical stability after 60 days of preparation. Eugenol-loaded Eudragit RS100 nanocapsules may be further used for reducing dental sensitivity.
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