Indah Solihah, Herlina Herlina, Elisa Munirah, Hesty Haryanti, Mustika Amalia, Riana Sari Puspita Rasyid, Tri Suciati, Fatma Fatma
{"title":"The hypoglycemic effect of purple sweet potato leaf fractions in diabetic rats","authors":"Indah Solihah, Herlina Herlina, Elisa Munirah, Hesty Haryanti, Mustika Amalia, Riana Sari Puspita Rasyid, Tri Suciati, Fatma Fatma","doi":"10.51847/rqsvc5gzwg","DOIUrl":null,"url":null,"abstract":"There is considerable interest in herbal medicine in developing antidiabetic alternative therapy based on plant-derived compounds that would reduce oral hypoglycemic agent-related adverse effects. Ipomoea batatas L. leaf has been reported as rich in phenolic compounds that can reduce the hyperglycemic condition. Research on the hypoglycemic effect of I. batatas L. leaf fraction in alloxan-induced diabetic rats has been conducted. Fractionation methods included gradual maceration with n-hexane, ethyl acetate, and ethanol. The diabetic condition was used alloxan intraperitoneally in rats until blood glucose levels reached > 200mg/dL. Rats were divided into 12 groups that are normal control, diabetic control, insulin treatment, n-hexane fraction (HF), ethyl acetate fraction (EAF), and ethanol fraction (EF) with doses of 50, 100, and 200 mg/kg BW, respectively. Blood glucose level and pancreatic homogenate MDA level were evaluated","PeriodicalId":37660,"journal":{"name":"Journal of Advanced Pharmacy Education and Research","volume":"12 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Advanced Pharmacy Education and Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.51847/rqsvc5gzwg","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
There is considerable interest in herbal medicine in developing antidiabetic alternative therapy based on plant-derived compounds that would reduce oral hypoglycemic agent-related adverse effects. Ipomoea batatas L. leaf has been reported as rich in phenolic compounds that can reduce the hyperglycemic condition. Research on the hypoglycemic effect of I. batatas L. leaf fraction in alloxan-induced diabetic rats has been conducted. Fractionation methods included gradual maceration with n-hexane, ethyl acetate, and ethanol. The diabetic condition was used alloxan intraperitoneally in rats until blood glucose levels reached > 200mg/dL. Rats were divided into 12 groups that are normal control, diabetic control, insulin treatment, n-hexane fraction (HF), ethyl acetate fraction (EAF), and ethanol fraction (EF) with doses of 50, 100, and 200 mg/kg BW, respectively. Blood glucose level and pancreatic homogenate MDA level were evaluated
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Journal of Advanced Pharmacy Education & Research [JAPER] aims to explore the knowledge of pharmacy professionals and cater the need of research and development activities of both academia and Industries. Further, also aimed to bridge the gap between theoretical aspects of drug delivery concepts and practical clinical studies to make sure of the novel drug delivery system usefulness in health care system. The Journal having scope for researchers engaged in drug delivery field to utilize the scientific contents in a rightful way. Journal of Advanced Pharmacy Education & Research [JAPER], a broad-based journal was founded on two key tenets: To publish the most exciting researches with respect to the subjects of Pharmaceutical science. Secondly, to provide a rapid turn-around time possible for reviewing and publishing, and to disseminate the articles freely for research, teaching and reference purposes. Our objective is to inform authors of the decision on their manuscript as early as possible. Following acceptance, a paper will normally be published in the next available issue. Journal of Advanced Pharmacy Education & Research [JAPER], is using online manuscript submission, review and tracking system for quality and quick review processing. Review processing is performed by the editorial board members of JAPER, outside experts; at least two independent reviewers approval followed by editor approval is required for acceptance of any citable manuscript.
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