The curious case of commitment to religion and prayer in extreme long term survival anaplastic astrocytoma patient

Goran Tasić, Igor Nikolić, Lukas Rasulić, Aleksandar Janićijević, Vuk Aleksić
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 We present a case of a male patient who is alive 25 years after the initial diagnosis and treatment of anaplastic astrocytoma WHO grade 3. The patient was operated and reoperated two times due to local tumour recurrence in the first two years after the initial diagnosis. After the last operation, the patient abandoned medical therapy and started praying. The patient is still alive without any clinical or radiological signs of tumour recurrence.","PeriodicalId":30188,"journal":{"name":"Romanian Neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Romanian Neurosurgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33962/roneuro-2023-019","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract

Anaplastic astrocytoma WHO (World Health Organization) grade 3 represents about 7% of all primary brain tumours in the adult population. The standard treatment protocol involves safe surgical resection, chemotherapy and radiotherapy. Advances in therapeutic protocols have been noted over the past few decades, but the prognoses are still poor with a median survival of 31 months. We present a case of a male patient who is alive 25 years after the initial diagnosis and treatment of anaplastic astrocytoma WHO grade 3. The patient was operated and reoperated two times due to local tumour recurrence in the first two years after the initial diagnosis. After the last operation, the patient abandoned medical therapy and started praying. The patient is still alive without any clinical or radiological signs of tumour recurrence.
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极端长期生存的间变性星形细胞瘤患者对宗教和祈祷的承诺的奇怪案例
世界卫生组织(WHO)三级间变性星形细胞瘤约占成人原发性脑肿瘤的7%。标准的治疗方案包括安全的手术切除、化疗和放疗。在过去的几十年里,治疗方案已经取得了进展,但预后仍然很差,中位生存期为31个月。我们报告了一例男性患者,他在最初诊断和治疗间变性星形细胞瘤who 3级后存活了25年。患者在最初诊断后的两年内因局部肿瘤复发而进行了两次手术和再手术。最后一次手术后,病人放弃了药物治疗,开始祈祷。患者仍然活着,没有任何肿瘤复发的临床或放射学迹象。
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