Perspectives of computational fluid dynamics methods in the study of membrane processes

A. I. Klyuchnikov, V. Y. Ovsyannikov, D. V. Klyuchnikova, A. M. Davydov
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Abstract

In mathematical modeling of membrane processes, the study of structural features of used membranes and the significant limitation of information in the formal description of their separation properties led to the development of physical models that take into account not only the features of structures of real membranes, but also their peculiarities of functioning. When compiling physical models of membrane processes, it is impossible to objectively quantify most of the factors due to their great diversity and variability, which distances the mathematical model from the real process. That is why methods of computational fluid dynamics reliably and efficiently perform calculations for all physical models and types, including stationary or transient flow, incompressible or compressible flow (from small subsonic to hypersonic), simulation of laminar or turbulent flows, Newtonian or non-Newtonian fluids, ideal or real gas. An electronic geometric model of the plant was built, a choice of mesh geometry with different densities was made to optimize the calculation time and solution accuracy for a particular case, the kinetic dependence of cell growth was calculated, the flow rates of feeding medium into the intra- and inter-fiber spaces of the bioreactor were determined, and the hydrodynamic conditions were analyzed.
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计算流体力学方法在膜过程研究中的展望
在膜过程的数学建模中,对使用过的膜的结构特征的研究以及对其分离特性的形式化描述中信息的显著限制导致了物理模型的发展,这些模型不仅考虑了真实膜的结构特征,而且考虑了它们的功能特性。在编制膜过程物理模型时,由于其多样性和可变性,大多数因素无法客观量化,这使得数学模型与实际过程有一定距离。这就是为什么计算流体动力学方法可靠而有效地执行所有物理模型和类型的计算,包括静止或瞬态流动,不可压缩或可压缩流动(从小亚音速到高超音速),层流或湍流模拟,牛顿或非牛顿流体,理想或真实气体。建立了生物反应器的电子几何模型,针对具体情况选择了不同密度的网格几何形状以优化计算时间和求解精度,计算了细胞生长的动力学依赖性,确定了进料介质进入生物反应器纤维内和纤维间空间的流速,并分析了流体动力学条件。
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发文量
70
审稿时长
8 weeks
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