Analysis of the Efficacy of Neuroendoscopic Hematoma Evacuation in the Treatment of Chronic Subdural Hematoma and its Influence on the Neurological Function of Patients

Chun Dong, Jun Jia, Wei Meng
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Abstract

Objective: To analyze the effect of neuroendoscopic hematoma evacuation on neurological function in patients with chronic subdural hematoma (CSDH). Methods: From September 2019 to September 2022, 113 patients with CSDH were selected and randomly divided into group A for neuroendoscopic hematoma evacuation and group B for soft channel drainage. The differences in neurological function of these two groups were compared. Results: Except for intraoperative blood loss and duration of surgery, all surgical indicators in group A were better than those in group B , P < 0.05. One month after operation, the neurological deficit (CSS) score in group A was lower than that in group B, and the quality of life (SF-36), activities of daily living (ADL) scores were higher than those in group B, with P < 0.05. 7 days after operation, the scores of superoxide dismutase (SOD), malondialdehyde (MDA), glutathione peroxidase (GSH-Px) and other oxidative stress indicators were better than those in group B, P < 0.05; the complication rate in group A was lower than that in group B, with P < 0.05. Conclusion: Neuroendoscopic hematoma evacuation therapy can regulate oxidative stress indicators, improve nerve defects, and improve the outcome of CSDH patients.
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神经内镜下血肿清除术治疗慢性硬膜下血肿的疗效及对患者神经功能的影响分析
目的:分析神经内镜下血肿清除术对慢性硬膜下血肿(CSDH)患者神经功能的影响。方法:选取2019年9月~ 2022年9月收治的CSDH患者113例,随机分为神经内镜血肿引流组和软通道引流组。比较两组患者神经功能的差异。结果:除术中出血量、手术时间外,A组各手术指标均优于B组,P <0.05. 术后1个月,A组患者的神经功能缺损(CSS)评分低于B组,生活质量(SF-36)、日常生活活动(ADL)评分高于B组,P <0.05. 术后7 d,超氧化物歧化酶(SOD)、丙二醛(MDA)、谷胱甘肽过氧化物酶(GSH-Px)等氧化应激指标评分均优于B组、P组和lt组;0.05;A组并发症发生率低于B组,P < 0.05;0.05. 结论:神经内镜下血肿排空治疗可调节氧化应激指标,改善神经缺损,改善CSDH患者预后。
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