Insulin Resistance in Association with Metabolic Syndrome in Wasit University Students in Iraq

Q3 Pharmacology, Toxicology and Pharmaceutics Iraqi Journal of Pharmaceutical Sciences Pub Date : 2023-09-27 DOI:10.31351/vol32iss2pp65-73
Alaa Zamil, Seenaa Amin
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Abstract

In Iraq 1.4 million of people have diabetes, the prevalence of T2DM was ranged (8.5%—13.9%), and the cluster of metabolic abnormalities has long been identified as the risk factors for type 2 diabetes and is now commonly described as metabolic syndrome/MetS. Insulin resistance takes a key role in the process of the MetS and has even been hypothesized as its underlying cause. Clinical and epidemiologic studies also indicate that obesity and life style habit might be correlated with IR. This study examined the relationship between IR and MetS in a sample of young, healthy university students in Iraq. It discovered that the severity of IR is positively correlated with the clustering of MetS risk factors in Iraqi students, suggesting that the IR index could be used as a diagnostic tool to identify the young adult who is at higher risk of developing IR and help prevent metabolic disorders that may develop secondary to IR. Insulin resistance was highly correlated with dietary product use, high BMI, and physical inactivity, investigating the IR in an early stage is crucial for trying to stop the disease progression into chronic disease.
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伊拉克Wasit大学学生胰岛素抵抗与代谢综合征的关系
在伊拉克,有140万人患有糖尿病,2型糖尿病的患病率在8.5%-13.9%之间,代谢异常群长期以来被确定为2型糖尿病的危险因素,现在通常被描述为代谢综合征/MetS。胰岛素抵抗在代谢过程中起着关键作用,甚至被假设为其潜在原因。临床和流行病学研究也表明,肥胖和生活方式习惯可能与IR有关。本研究考察了伊拉克年轻健康大学生IR和met之间的关系。研究发现,IR的严重程度与伊拉克学生的met风险因素聚类呈正相关,这表明IR指数可以作为一种诊断工具,用于识别患IR风险较高的年轻人,并有助于预防可能继发于IR的代谢紊乱。胰岛素抵抗与饮食产品使用、高BMI和缺乏身体活动高度相关,在早期研究IR对于试图阻止疾病进展为慢性疾病至关重要。
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来源期刊
Iraqi Journal of Pharmaceutical Sciences
Iraqi Journal of Pharmaceutical Sciences Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
1.40
自引率
0.00%
发文量
37
审稿时长
24 weeks
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