Larissa Lea da Silva, Marcelo Dutra Duque, Michele Georges Issa, Leticia Norma Carpentieri Rodrigues
{"title":"Isosorbide Dinitrate Orally Disintegrating Films Cyclodextrins/HPMC Based: Mechanical, Optical, and Physicochemical Studies","authors":"Larissa Lea da Silva, Marcelo Dutra Duque, Michele Georges Issa, Leticia Norma Carpentieri Rodrigues","doi":"10.1590/1678-4324-2023220370","DOIUrl":null,"url":null,"abstract":"HIGHLIGHTS Orally films Cyclodextrins/HPMC based films were prepared by solvent casting. Films for oral delivery of ISDN were prepared by 32 factorial designs. Mechanical, optical, and dissolution properties were evaluated. The experimental design allowed to optimize the formulations. The best formulation was obtained by means of the desirability function.","PeriodicalId":9169,"journal":{"name":"Brazilian Archives of Biology and Technology","volume":"45 1","pages":"0"},"PeriodicalIF":1.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brazilian Archives of Biology and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1590/1678-4324-2023220370","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
HIGHLIGHTS Orally films Cyclodextrins/HPMC based films were prepared by solvent casting. Films for oral delivery of ISDN were prepared by 32 factorial designs. Mechanical, optical, and dissolution properties were evaluated. The experimental design allowed to optimize the formulations. The best formulation was obtained by means of the desirability function.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
