Myeloid Sarcoma: Case Series with Unusual Locations

Akram Abedi, Nasrin Namdari, Ahmad Monabati, Akbar Safaei, Parvin Rajabi, Maral Mokhtari
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Abstract

Myeloid sarcoma (MS) or chloroma is a localized mass composed of blastic cells of granulocytic lineage. It is a subtype of acute myeloid leukemia and usually presents as a complication of acute myeloid leukemia, myeloid dysplastic syndrome, or myeloproliferative disorder. MS occurs in 2.5-9.1% of patients with AML, precedes the clinical disease, coincidence with the onset or at relapse and in rare conditions, it can occur with no evidence of hematologic disorders. Here, we presented seven cases of MS in unusual locations or with rare presentations at presentation or relapse. We concluded that MS should be considered in the differential diagnosis of any high-grade tumor, especially in a patient with previous history of any myeloid neoplasm.
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髓系肉瘤:具有异常位置的病例系列
髓样肉瘤(MS)或氯瘤是由粒细胞系的母细胞组成的局部肿块。它是急性髓性白血病的一种亚型,通常表现为急性髓性白血病、骨髓发育不良综合征或骨髓增生性疾病的并发症。多发性硬化症发生在2.5-9.1%的急性髓系白血病患者中,在临床发病之前,与发病或复发同时发生,在罕见的情况下,它可以在没有血液系统疾病证据的情况下发生。在这里,我们提出了7例多发性硬化症在不寻常的位置或罕见的表现或复发。我们的结论是,在任何高级别肿瘤的鉴别诊断中,特别是在既往有任何髓系肿瘤病史的患者中,都应考虑MS。
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