Effects of Health Education on Knowledge, Attitude and Practice of Adverse Drug Reaction Reporting among Community Pharmacists in Anambra State, Nigeria

Churchhill O. Osagie, Chinomnso C. Nnebue, Chijioke A. Ezenyeaku, Martin N. Okolie, Abuchi E. Nwafia, Ifeoma B. Udigwe, Achunam S. Nwabueze, Chika F. Ubajaka
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Abstract

Background: Poor reportage of adverse drug reaction has been linked o. increase in morbidity, mortality and economic burden of diseases and health related conditions. Objective: To determine the effects of health education on knowledge, attitude and practice of adverse drug reaction (ADR) reporting among community pharmacists practicing in Anambra State. Methods: This interventional study was conducted among Community Pharmacists in Anambra State. Simple random samp\ling technique was used. Pre-tested, semi-structured self-administered questionnaire was used to collect data on respondents’ socio-demographics, knowledge of, attitude to and practice of ADR reporting Associations between variables were tested using Chi-square and Binary logistic regression at 5% level of significance. Data obtained were analyzed using SPSS version 23. Results: The mean age of the respondents was 46.5±11.2 years. Post intervention result shows that there was an increase in knowledge of ADR reporting in the intervention group from 52% to 95.3%. There was a decrease in knowledge of ADRs reporting in the control group from 47.3% to44.7%. There was a statistically significant difference between the experimental group and the control group on their attitude towards ADR reporting (p<0.05). Only 26.7% of the test group had filled a spontaneous reporting ADR form prior to this study compared to 18% from the control group and is associated with the effect of health education intervention. Conclusions: There was underreporting of ADRs, associated with gaps in the knowledge, attitude and practice among the community pharmacists studied. There is need for focused continuous health education interventions on ADR reporting among them.
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健康教育对尼日利亚阿南布拉州社区药师药物不良反应报告知识、态度和行为的影响
背景:药物不良反应报告不足与疾病和健康相关病症的发病率、死亡率和经济负担增加有关。 目的:了解健康教育对阿南布拉州执业社区药师药品不良反应(ADR)报告知识、态度和行为的影响。方法:对阿南布拉州社区药师进行介入研究。采用简单随机抽样技术。采用预测的半结构化自填问卷收集调查对象的社会人口统计学、不良反应报告的知识、态度和实践等方面的数据。变量之间的关联采用卡方和二元logistic回归进行检验,显著性水平为5%。获得的数据使用SPSS version 23进行分析。 结果:调查对象平均年龄为46.5±11.2岁。干预后结果显示,干预组对不良反应报告的知晓率由52%提高到95.3%。对照组对不良反应报告的知晓率从47.3%降至44.7%。实验组与对照组对不良反应报告的态度差异有统计学意义(p < 0.05)。在这项研究之前,实验组中只有26.7%的人填写了自发报告不良反应表格,而对照组中这一比例为18%,这与健康教育干预的效果有关。 结论:所研究的社区药师存在不良反应的少报现象,这与他们的知识、态度和实践存在差距有关。有必要重点开展持续的健康教育干预措施,促进他们报告不良反应。
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