Diagnostic difficulties in a very rare case of mycoplasma pneumoniae uveitis

Q4 Pharmacology, Toxicology and Pharmaceutics Acta Marisiensis - Seria Medica Pub Date : 2023-09-01 DOI:10.2478/amma-2023-0035
Ana-Maria-Catalina Hadad, Florina Vultur, Marius-Alexandru Beleaua, Karin Horvath
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Abstract

Abstract Introduction : Mycoplasma pneumoniae is known as a common cause of respiratory tract infections, especially in children. Regarding extrapulmonary manifestations, many dysfunctions have been linked to circulating IgM antibodies, including eye diseases and disorders. In this report, we aim to highlight the importance of considering Mycoplasma pneumoniae a potential etiological agent that can cause significant eye structures inflammation. Case presentation : We present a case of a 22-year-old male patient who arrived at the Emergency Department complaining of visual acuity decrement. Fundoscopic examination outlined a pale optic nerve, covered by pre-papillary infiltrates and peripheric inflammatory infiltrates, accompanied by signs of vasculitis. Investigations were performed and a multidisciplinary assessment was conducted. General antibiotic and antimycotic treatment and topical non-steroidal anti-inflammatory drops were administrated but his symptoms were aggravating, although it was continuously upgraded. Antibodies for Mycoplasma pneumoniae were determined with positive IgM and macrolide antibiotherapy was administrated, with favorable evolution. Conclusions : Mycoplasma pneumoniae should not be excluded as a possible cause of severe ocular inflammations, even in asymptomatic patients. The patient’s management should include multidisciplinary assessment for an easier diagnosis in cases of uncertainty.
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非常罕见的肺炎支原体葡萄膜炎病例诊断困难
摘要简介:肺炎支原体被认为是呼吸道感染的常见原因,尤其是在儿童中。关于肺外表现,许多功能障碍与循环IgM抗体有关,包括眼病和疾病。在本报告中,我们的目的是强调考虑肺炎支原体是一种潜在的病原体的重要性,它可以引起显著的眼睛结构炎症。病例介绍:我们报告一个22岁的男性病人到急诊科抱怨视力下降。眼底镜检查显示浅色视神经,被乳头前浸润和周围炎性浸润所覆盖,并伴有血管炎征象。进行了调查并进行了多学科评估。给予一般抗生素和抗真菌治疗和局部非甾体抗炎滴剂,但他的症状不断加重,尽管病情不断升级。肺炎支原体抗体检测IgM阳性,给予大环内酯类抗生素治疗,进展良好。结论:即使在无症状的患者中,也不应排除肺炎支原体作为严重眼部炎症的可能原因。患者的管理应包括多学科评估,以便在不确定的情况下更容易诊断。
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来源期刊
Acta Marisiensis - Seria Medica
Acta Marisiensis - Seria Medica Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
0.40
自引率
0.00%
发文量
0
审稿时长
24 weeks
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