Experience in surgical treatment of extra-intracranial tandem ICA stenosis at the National Medical Research Center for High Medical Technologies named after A. A. Vishnevsky of the Ministry of Defense of the Russian Federation

A.V. Fedyanin, G.I. Antonov, E.G. Chmutin, G.E. Chmutin, E.R. Miklashevich, S.Yu. Gladyshev, I.I. Shumakov, S.V. Melnichuk, M.M. Muminzhonova
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Abstract

To date, the effectiveness and safety of reconstructive surgery for steno-occlusive lesions of the internal carotid artery (ICA) have been proven by multicenter cooperative studies Despite this, the indications and tactics of surgical treatment of patients with extra-intracranial tandem stenotic lesions of the ICA remain controversial. In the period 2010-2020, 32 patients with symptomatic (15 cases) and asymptomatic tandem ICA lesions were hospitalized for surgical treatment. The distribution of tandem lesions was as follows: 10 patients had bicarotid hemodynamically significant stenotic and occlusive lesions of the ICA ostium in combination with stenosis of more than 50% of the petrous (4 cases), cavernous (8 cases), and clinoid segments (5 cases), of these, four had bilateral intracranial stenosis; 22 patients with hemodynamically significant lesions of the ICA and vertebral artery (VA) in combination with stenosis of more than 50% of the petrous (10 cases), foramen lacerum (2 cases), cavernous (16 cases), clinoid (14 cases), and ophthalmic segments (1 cases), of these, six had bilateral intracranial stenosis of the ICA. All patients underwent staged surgical interventions on the arteries of the carotid and vertebrobasilar systems. In the postoperative period, there was one case of repeated ischemic stroke in the territory of the reconstructed artery after the application of extra-intracranial microanastomosis (EICMA). There were no relapses of restenosis or acute cerebrovascular accident (CVA) in the follow-up. Staged reconstructive and revascularization treatment is safe and effective for tandem extra-intracranial lesions of the ICA. It is necessaryto continue further study of this issue in order to develop unified tactics and methods of surgical treatment.
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在以俄罗斯联邦国防部A. A. Vishnevsky命名的国家高医疗技术医学研究中心进行颅内外串联ICA狭窄手术治疗的经验
迄今为止,多中心合作研究已证实颈内动脉(ICA)狭窄闭塞病变重建手术的有效性和安全性。尽管如此,颅内外颈内动脉连续狭窄病变患者的手术治疗指征和策略仍存在争议。2010-2020年期间,32例有症状(15例)和无症状的串联ICA病变住院接受手术治疗。继发性病变的分布如下:10例患者存在颈动脉血流动力学显著的ICA口狭窄闭塞病变,合并岩状节段(4例)、海绵状节段(8例)、斜状节段(5例)的狭窄超过50%,其中4例为双侧颅内狭窄;22例颈内动脉及椎动脉(VA)血流动力学显著病变合并岩状(10例)、撕裂孔(2例)、海绵状(16例)、斜状(14例)、眼段(1例)狭窄超过50%,其中6例颈内动脉双侧颅内狭窄。所有患者都接受了分阶段的颈动脉和椎基底动脉系统的手术干预。术后应用颅内外微吻合术(EICMA)后,重建动脉区域发生反复缺血性脑卒中1例。随访无再狭窄复发及急性脑血管意外(CVA)。分阶段重建和血运重建术治疗颈内动脉颅内多发病变是安全有效的。为了制定统一的手术治疗策略和方法,有必要继续深入研究这一问题。
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