The effects of boron trioxide on the structure and degradation behaviour of borosilicate bioactive glass

IF 2.9 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Materials Technology Pub Date : 2023-04-07 DOI:10.1080/10667857.2023.2199581
Minhui Zhang, Jian Lin, Song Ye, Deping Wang, Aihua Yao, Xuanyu Zhang, Rui Wu, Chengyun Jin
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引用次数: 1

Abstract

Degradation behaviour of bioactive glass (bioglass) is one of the most important factors affecting bone repair, because an excellent and controllable degradation rate can match the rate of new bone formation. In this research, the derived borosilicate bioglasses based on the 6Na2O-8K2O-8MgO-22CaO-18B2O3-54SiO2-2P2O5 component were synthesized. The effects of B2O3 on the structure, degradation behaviour and cytocompatibility of borosilicate bioglasses were systematically studied. The results showed that with B2O3 addition, the network-forming units became diversified and part of BO4 units transformed into BO3 units. These factors weakened the chemical durability of borosilicate bioglass, thus accelerating the bioglass shedding and altering the ions release, especially B. This study provides a theoretical basis for designing borosilicate bioglass with adjustable degradation rate and ion release behaviour to meet the diverse needs of clinical bone repair.
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三氧化二硼对硼硅酸盐生物活性玻璃结构及降解行为的影响
生物活性玻璃的降解行为是影响骨修复的最重要因素之一,因为良好的可控制的降解率可以匹配新骨形成的速度。本研究合成了基于6na20 - 8k20 - 8mgo - 22cao - 18b2o3 - 54sio2 - 2p2o5组分的衍生硼硅酸盐生物玻璃。系统研究了B2O3对硼硅酸盐生物玻璃的结构、降解行为和细胞相容性的影响。结果表明:随着B2O3的加入,形成网络的单元变得多样化,部分BO4单元转变为BO3单元;这些因素削弱了硼硅生物玻璃的化学耐久性,从而加速了生物玻璃的脱落,改变了离子的释放,尤其是b离子的释放。本研究为设计具有可调节降解速率和离子释放行为的硼硅生物玻璃,满足临床骨修复的多样化需求提供了理论基础。
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来源期刊
Materials Technology
Materials Technology 工程技术-材料科学:综合
CiteScore
6.00
自引率
9.70%
发文量
105
审稿时长
8.7 months
期刊介绍: Materials Technology: Advanced Performance Materials provides an international medium for the communication of progress in the field of functional materials (advanced materials in which composition, structure and surface are functionalised to confer specific, applications-oriented properties). The focus is on materials for biomedical, electronic, photonic and energy applications. Contributions should address the physical, chemical, or engineering sciences that underpin the design and application of these materials. The scientific and engineering aspects may include processing and structural characterisation from the micro- to nanoscale to achieve specific functionality.
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