The interest of intranasal clonidine in the prevention of perioperative children's anxiety: a prospective randomized trial

Mariem Keskes, Nouha Amouri, Salma Ketata, Rahma Derbel, Maha Charfi, Imen Zouche, Moncef Sallemi, Moez Elloumi, Hichem Chikhrouhou
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Abstract

Introduction: perioperative anxiety in children may lead to psychological and physiological side effects. Clonidine is in increasing use in the pediatric population as an anxiolytic, sedative, and analgesic because of its central alpha2-adrenergic agonist effect. Our study aimed to evaluate the effect of clonidine in the prevention of perioperative children´s anxiety.
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鼻内可乐定在预防围手术期儿童焦虑中的作用:一项前瞻性随机试验
儿童围手术期焦虑可能导致心理和生理上的副作用。由于其中枢α 2-肾上腺素能激动剂作用,可乐定在儿科人群中作为抗焦虑、镇静和镇痛药的使用越来越多。本研究旨在评价可乐定对围手术期儿童焦虑的预防作用。
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